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quetiapine fumarate or valproate — Competitive Intelligence Brief
phase 3
Atypical antipsychotic + anticonvulsant mood stabilizer combination
Dopamine receptors (D2), serotonin receptors (5-HT1A, 5-HT2A); GABA pathway, histone deacetylase
Psychiatry
Small molecule
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Target snapshot
quetiapine fumarate or valproate (quetiapine fumarate or valproate) — AstraZeneca. This is a combination of two distinct psychiatric medications: quetiapine fumarate (an atypical antipsychotic) and valproate (a mood stabilizer), each working through different neurochemical pathways.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| quetiapine fumarate or valproate TARGET | quetiapine fumarate or valproate | AstraZeneca | phase 3 | Atypical antipsychotic + anticonvulsant mood stabilizer combination | Dopamine receptors (D2), serotonin receptors (5-HT1A, 5-HT2A); GABA pathway, histone deacetylase | |
| Quetiapine and Topiramate | Quetiapine and Topiramate | University of Cincinnati | marketed | Atypical antipsychotic + anticonvulsant mood stabilizer combination | D2 dopamine receptor, 5-HT2A serotonin receptor (quetiapine); voltage-gated sodium channels, carbonic anhydrase (topiramate) | |
| Risperidone, divalproex | Risperidone, divalproex | Nathan Kline Institute for Psychiatric Research | marketed | Atypical antipsychotic + anticonvulsant mood stabilizer combination | Dopamine D2 receptor (risperidone); histone deacetylase / GABA pathway (divalproex) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Atypical antipsychotic + anticonvulsant mood stabilizer combination class)
- AstraZeneca · 1 drug in this class
- Nathan Kline Institute for Psychiatric Research · 1 drug in this class
- University of Cincinnati · 1 drug in this class
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Cite this brief
Drug Landscape (2026). quetiapine fumarate or valproate — Competitive Intelligence Brief. https://druglandscape.com/ci/quetiapine-fumarate-or-valproate. Accessed 2026-05-17.
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