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Purinostat Mesylate for Injection — Competitive Intelligence Brief
phase 3
Histone deacetylase inhibitor
Histone deacetylases
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Purinostat Mesylate for Injection (Purinostat Mesylate for Injection) — Chengdu Zenitar Biomedical Technology Co., Ltd. Purinostat Mesylate for Injection is a histone deacetylase inhibitor that works by blocking the activity of histone deacetylases, leading to the accumulation of acetylated histones and changes in gene expression.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Purinostat Mesylate for Injection TARGET | Purinostat Mesylate for Injection | Chengdu Zenitar Biomedical Technology Co., Ltd | phase 3 | Histone deacetylase inhibitor | Histone deacetylases | |
| Chidamide+ Fulvestrant | Chidamide+ Fulvestrant | Liaoning Cancer Hospital & Institute | marketed | HDAC inhibitor + selective estrogen receptor degrader (combination therapy) | Histone deacetylases (HDAC) + Estrogen receptor alpha (ERα) | |
| Low dose valproate | Low dose valproate | Mario Negri Institute for Pharmacological Research | marketed | Histone deacetylase (HDAC) inhibitor | Histone deacetylases (HDACs) | |
| Vorinostat (VOR) | Vorinostat (VOR) | University of North Carolina, Chapel Hill | marketed | Histone deacetylase (HDAC) inhibitor | Histone deacetylases (HDAC1, HDAC2, HDAC3, HDAC6, HDAC8) | |
| placebo to vorinostat | placebo to vorinostat | Merck Sharp & Dohme LLC | phase 3 | Histone deacetylase inhibitor | Histone deacetylases | |
| Romidepsin + CHOP | Romidepsin + CHOP | The Lymphoma Academic Research Organisation | phase 3 | HDAC inhibitor + chemotherapy combination | Histone deacetylases (HDAC) | |
| SHR2554 analog tablets; Chidamide | SHR2554 analog tablets; Chidamide | Jiangsu HengRui Medicine Co., Ltd. | phase 3 | Histone deacetylase inhibitor | Histone deacetylases |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Histone deacetylase inhibitor class)
- Celgene · 1 drug in this class
- Chengdu Zenitar Biomedical Technology Co., Ltd · 1 drug in this class
- Evopoint Biosciences Inc. · 1 drug in this class
- Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
- Medical University of Vienna · 1 drug in this class
- Merck Sharp & Dohme LLC · 1 drug in this class
- NCIC Clinical Trials Group · 1 drug in this class
- PharmaMar · 1 drug in this class
- Telik · 1 drug in this class
- Tianjin Medical University Cancer Institute and Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Purinostat Mesylate for Injection — Competitive Intelligence Brief. https://druglandscape.com/ci/purinostat-mesylate-for-injection. Accessed 2026-05-16.
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