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PTC923 — Competitive Intelligence Brief

PTC923 (PTC923) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Pyruvate dehydrogenase kinase (PDK) inhibitor. Area: Rare genetic/metabolic disorders.

phase 3 Pyruvate dehydrogenase kinase (PDK) inhibitor PDK (pyruvate dehydrogenase kinase) Rare genetic/metabolic disorders Small molecule Live · refreshed every 30 min

Target snapshot

PTC923 (PTC923) — PTC Therapeutics. PTC923 is a small-molecule inhibitor of pyruvate dehydrogenase kinase (PDK) that restores pyruvate dehydrogenase (PDH) activity to improve mitochondrial energy metabolism.

Comparator set (1 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
PTC923 TARGET PTC923 PTC Therapeutics phase 3 Pyruvate dehydrogenase kinase (PDK) inhibitor PDK (pyruvate dehydrogenase kinase)
DBPR108 DBPR108 National Health Research Institutes, Taiwan phase 3 Pyruvate dehydrogenase kinase (PDK) inhibitor PDK (Pyruvate Dehydrogenase Kinase)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Pyruvate dehydrogenase kinase (PDK) inhibitor class)

  1. National Health Research Institutes, Taiwan · 1 drug in this class
  2. PTC Therapeutics · 1 drug in this class

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Cite this brief

Drug Landscape (2026). PTC923 — Competitive Intelligence Brief. https://druglandscape.com/ci/ptc923. Accessed 2026-05-13.

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