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Prostaglandin E2 — Competitive Intelligence Brief
marketed
Prostaglandin analog
Prostaglandin E receptors (EP1, EP2, EP3, EP4)
Multiple (Obstetrics, Gastroenterology, Rheumatology)
Small molecule
Live · refreshed every 30 min
Target snapshot
Prostaglandin E2 (Prostaglandin E2) — Shaare Zedek Medical Center. Prostaglandin E2 (PGE2) binds to prostaglandin E receptors (EP1-EP4) on cell surfaces to modulate inflammation, smooth muscle contraction, and various physiological processes.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Prostaglandin E2 TARGET | Prostaglandin E2 | Shaare Zedek Medical Center | marketed | Prostaglandin analog | Prostaglandin E receptors (EP1, EP2, EP3, EP4) | |
| Lumigan | BIMATOPROST | marketed | Prostaglandin Analog [EPC] | Aldo-keto reductase family 1 member C3 | 2001-01-01 | |
| Travatan | TRAVOPROST | marketed | Prostaglandin Analog [EPC] | Prostaglandin F2-alpha receptor | 2001-01-01 | |
| Xalatan | LATANOPROST | Thea Pharma | marketed | Prostaglandin Analog [EPC] | Prostaglandin F2-alpha receptor | 1996-01-01 |
| Cytotec | Misoprostol | Pfizer | marketed | NSAID combined with prostaglandin analog | Cyclooxygenase (COX-1 and COX-2); Prostaglandin receptors | 1988-01-01 |
| Caverject | ALPROSTADIL | Pfizer | marketed | Prostaglandin Analog [EPC] | Prostaglandin E2 receptor EP3 subtype | 1981-01-01 |
| Hemabate | CARBOPROST | Pfizer | marketed | Prostaglandin Analog | Prostaglandin F2-alpha receptor | 1979-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Prostaglandin analog class)
- Allergan · 3 drugs in this class
- AbbVie · 2 drugs in this class
- Bnai Zion Medical Center · 1 drug in this class
- Ibis Reproductive Health · 1 drug in this class
- Ocuwize LTD · 1 drug in this class
- Shaare Zedek Medical Center · 1 drug in this class
- University Medical Centre Maribor · 1 drug in this class
- University of North Carolina, Chapel Hill · 1 drug in this class
- University of Pennsylvania · 1 drug in this class
- Wolfson Medical Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Prostaglandin E2 — Competitive Intelligence Brief. https://druglandscape.com/ci/prostaglandin-e2. Accessed 2026-05-13.
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