Who are propofol (drug)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): SAGE-547, Sevoflurane + Remifentanyl, intravenous sedation with propofol, Sevoflurane intravenous anesthesia, Propofol-Lipuro, Remifentanil and/or propofol.

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Last reviewed 2026-06-09 · How we verify

propofol (drug) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

propofol (drug) (propofol (drug)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: GABA receptor agonist. Area: Anesthesiology.

phase 3 GABA receptor agonist GABA_A receptor Anesthesiology Small molecule Live · refreshed every 30 min

Target snapshot

propofol (drug) (propofol (drug)) — B. Braun Melsungen AG. Propofol is a short-acting sedative-hypnotic agent that acts on the central nervous system to induce and maintain anesthesia.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
propofol (drug) TARGET	propofol (drug)	B. Braun Melsungen AG	phase 3	GABA receptor agonist	GABA_A receptor
SAGE-547	SAGE-547	Supernus Pharmaceuticals, Inc.	phase 3	antisense oligonucleotide	GABA_A receptor alpha 1 subunit
Sevoflurane + Remifentanyl	Sevoflurane + Remifentanyl	Azienda Ospedaliera San Gerardo di Monza	phase 3	General anesthetic and opioid analgesic	GABA_A receptor and opioid receptors
intravenous sedation with propofol	intravenous sedation with propofol	University Hospital, Clermont-Ferrand	phase 3	GABA_A receptor agonist	GABA_A receptor
Sevoflurane intravenous anesthesia	Sevoflurane intravenous anesthesia	The Cleveland Clinic	phase 3	Volatile anesthetic	GABA_A receptor
Propofol-Lipuro	Propofol-Lipuro	University Hospital, Grenoble	phase 3	GABA receptor agonist	GABA_A receptor
Remifentanil and/or propofol	Remifentanil and/or propofol	Alder Hey Children's NHS Foundation Trust	phase 3	Opioid analgesic, Sedative-hypnotic	Opioid receptors, GABA_A receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (GABA receptor agonist class)

Amsterdam UMC, location VUmc · 1 drug in this class
B. Braun Melsungen AG · 1 drug in this class
Impax Laboratories, LLC · 1 drug in this class
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · 1 drug in this class
University Hospital, Grenoble · 1 drug in this class

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Cite this brief

Drug Landscape (2026). propofol (drug) — Competitive Intelligence Brief. https://druglandscape.com/ci/propofol-drug. Accessed 2026-06-09.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing