Last reviewed · How we verify

Primary Medical Treatment Pathway — Competitive Intelligence Brief

Primary Medical Treatment Pathway (Primary Medical Treatment Pathway) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: anti-VEGF agent. Area: Ophthalmology.

marketed anti-VEGF agent VEGF Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

Primary Medical Treatment Pathway (Primary Medical Treatment Pathway) — Moorfields Eye Hospital NHS Foundation Trust. This drug works by inhibiting the action of vascular endothelial growth factor (VEGF) to reduce angiogenesis.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Primary Medical Treatment Pathway TARGET Primary Medical Treatment Pathway Moorfields Eye Hospital NHS Foundation Trust marketed anti-VEGF agent VEGF
REGORAFENIB REGORAFENIB marketed RET, VEGFR1, VEGFR2, VEGFR3, KIT, PDGFR-alpha, PDGFR-beta, FGFR1, FGFR2, TIE2, DDR2, TrkA, Eph2A, RAF-1, BRAF, BRAF V600E, SAPK2, PTK5, Abl, CSF1R 2012-01-01
PONATINIB HYDROCHLORIDE PONATINIB HYDROCHLORIDE marketed ABL, T315I mutant ABL, VEGFR, PDGFR, FGFR, EPH receptors, SRC family, KIT, RET, TIE2, FLT3 2012-01-01
Inlyta Axitinib Pfizer marketed Receptor tyrosine kinase inhibitor Vascular endothelial growth factor receptors (VEGFR)-1, VEGFR-2, VEGFR-3 2012-01-01
PAZOPANIB PAZOPANIB marketed Kinase Inhibitor [EPC] VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-ɑ, PDGFR-β, FGFR-1, FGFR-3, Kit, Itk, Lck, c-Fms 2009-01-01
PAZOPANIB HYDROCHLORIDE PAZOPANIB HYDROCHLORIDE marketed VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-α, PDGFR-β, FGFR-1, FGFR-3, Kit, Itk, Lck, c-Fms 2009-01-01
Sutent Sunitinib Malate Pfizer marketed Small molecule kinase inhibitor Receptor tyrosine kinases (RTKs): PDGFRα, PDGFRβ, VEGFR1, VEGFR2, VEGFR3, KIT, FLT3, CSF-1R, RET 2006-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (anti-VEGF agent class)

  1. Hawaii Pacific Health · 1 drug in this class
  2. Jaeb Center for Health Research · 1 drug in this class
  3. Moorfields Eye Hospital NHS Foundation Trust · 1 drug in this class
  4. Novartis · 1 drug in this class
  5. ONL Therapeutics · 1 drug in this class

Subscribe to ongoing alerts

Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:

Cite this brief

Drug Landscape (2026). Primary Medical Treatment Pathway — Competitive Intelligence Brief. https://druglandscape.com/ci/primary-medical-treatment-pathway. Accessed 2026-05-17.

Build your own brief

Pick any drug + add comparators: