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Precedex (Dexmedetomidine) — Competitive Intelligence Brief
marketed
Alpha-2 adrenergic receptor agonist
Alpha-2 adrenergic receptor
Anesthesia/Sedation
Small molecule
Live · refreshed every 30 min
Target snapshot
Precedex (Dexmedetomidine) (Precedex (Dexmedetomidine)) — Icahn School of Medicine at Mount Sinai. Dexmedetomidine is a selective alpha-2 adrenergic receptor agonist that produces sedation, analgesia, and anxiolysis by activating presynaptic and postsynaptic alpha-2 receptors in the central nervous system.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Precedex (Dexmedetomidine) TARGET | Precedex (Dexmedetomidine) | Icahn School of Medicine at Mount Sinai | marketed | Alpha-2 adrenergic receptor agonist | Alpha-2 adrenergic receptor | |
| Norepinephrine (Levophed) | Norepinephrine (Levophed) | University of Louisville | marketed | Catecholamine; sympathomimetic amine | Alpha-1 adrenergic receptor; alpha-2 adrenergic receptor; beta-1 adrenergic receptor | |
| Nebulized lidocaine and dexmedetomidine | Nebulized lidocaine and dexmedetomidine | Ain Shams University | marketed | Local anesthetic and sedative-analgesic combination | Voltage-gated sodium channels (lidocaine); alpha-2 adrenergic receptors (dexmedetomidine) | |
| Dexmedetomidine 0.5 microgram/kg | Dexmedetomidine 0.5 microgram/kg | Sindh Institute of Urology and Transplantation | marketed | Alpha-2 adrenergic receptor agonist | Alpha-2 adrenergic receptor | |
| Escitalopram+Mirtazapine | Escitalopram+Mirtazapine | Ministry of Health & Welfare, Korea | marketed | Antidepressant combination (SSRI + NaSSA) | Serotonin transporter (SERT), norepinephrine transporter (NET), alpha-2 adrenergic receptors, histamine H1 receptors | |
| dexmedetomidine 1 µg/kg IV | dexmedetomidine 1 µg/kg IV | American University of Beirut Medical Center | marketed | Alpha-2 adrenergic agonist | Alpha-2 adrenergic receptor | |
| Catapresan TTS 2 | Catapresan TTS 2 | Heart Care Foundation | marketed | Central alpha-2 adrenergic agonist | Alpha-2 adrenergic receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Alpha-2 adrenergic receptor agonist class)
- Allergan · 3 drugs in this class
- Eye & ENT Hospital of Fudan University · 2 drugs in this class
- National Cancer Institute, Egypt · 2 drugs in this class
- The University of Hong Kong · 2 drugs in this class
- Sindh Institute of Urology and Transplantation · 2 drugs in this class
- Fayoum University Hospital · 1 drug in this class
- First Affiliated Hospital of Chongqing Medical University · 1 drug in this class
- Guangzhou General Hospital of Guangzhou Military Command · 1 drug in this class
- Icahn School of Medicine at Mount Sinai · 1 drug in this class
- KAT General Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Precedex (Dexmedetomidine) — Competitive Intelligence Brief. https://druglandscape.com/ci/precedex-dexmedetomidine. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing