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PQ (0.75) — Competitive Intelligence Brief

PQ (0.75) (PQ (0.75)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: 8-aminoquinoline antimalarial. Area: Infectious Disease / Parasitology.

phase 3 8-aminoquinoline antimalarial Plasmodium hypnozoite (liver stage parasite) Infectious Disease / Parasitology Small molecule Live · refreshed every 30 min

Target snapshot

PQ (0.75) (PQ (0.75)) — London School of Hygiene and Tropical Medicine. PQ is a primaquine analog that acts as an 8-aminoquinoline antimalarial targeting the hypnozoite stage of Plasmodium parasites in the liver.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
PQ (0.75) TARGET PQ (0.75) London School of Hygiene and Tropical Medicine phase 3 8-aminoquinoline antimalarial Plasmodium hypnozoite (liver stage parasite)
PQ supervised PQ supervised Menzies School of Health Research marketed 8-aminoquinoline antimalarial Plasmodium hypnozoites (mechanism not fully elucidated at molecular level)
PQ unsupervised PQ unsupervised Menzies School of Health Research marketed 8-aminoquinoline antimalarial Plasmodium hypnozoite mitochondria
Tafenoquine prophylaxis Tafenoquine prophylaxis Naval Medical Research Center marketed 8-aminoquinoline antimalarial Plasmodium mitochondrial electron transport chain
Supervised primaquine treatment Supervised primaquine treatment Menzies School of Health Research marketed 8-aminoquinoline antimalarial Plasmodium parasite mitochondria and DNA
Unsupervised primaquine treatment Unsupervised primaquine treatment Menzies School of Health Research marketed 8-aminoquinoline antimalarial Malaria parasite mitochondria and DNA (indirect via oxidative stress)
High dose ultra short Primaquine High dose ultra short Primaquine Menzies School of Health Research phase 3 8-aminoquinoline antimalarial Malaria parasite (Plasmodium spp.) — mechanism involves oxidative stress generation

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (8-aminoquinoline antimalarial class)

  1. Menzies School of Health Research · 5 drugs in this class
  2. London School of Hygiene and Tropical Medicine · 2 drugs in this class
  3. Naval Medical Research Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). PQ (0.75) — Competitive Intelligence Brief. https://druglandscape.com/ci/pq-0-75. Accessed 2026-05-15.

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