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PPI, amoxicillin, metronidazole and clarithromycin — Competitive Intelligence Brief
marketed
Antibiotic combination therapy with acid suppression
Helicobacter pylori (bacterial pathogen); PPI targets H+/K+-ATPase; amoxicillin targets bacterial cell wall; metronidazole and clarithromycin target bacterial protein synthesis
Gastroenterology / Infectious Disease
Small molecule
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Target snapshot
PPI, amoxicillin, metronidazole and clarithromycin (PPI, amoxicillin, metronidazole and clarithromycin) — Infante, Javier Molina, M.D.. This is a quadruple therapy regimen that eradicates Helicobacter pylori by combining acid suppression with three antibiotics that target bacterial protein synthesis and DNA.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| PPI, amoxicillin, metronidazole and clarithromycin TARGET | PPI, amoxicillin, metronidazole and clarithromycin | Infante, Javier Molina, M.D. | marketed | Antibiotic combination therapy with acid suppression | Helicobacter pylori (bacterial pathogen); PPI targets H+/K+-ATPase; amoxicillin targets bacterial cell wall; metronidazole and clarithromycin target bacterial protein synthesis | |
| PPI-amoxicillin-clarithromycin | PPI-amoxicillin-clarithromycin | National Taiwan University Hospital | marketed | Antibiotic combination therapy with acid suppression | Helicobacter pylori (bacterial pathogen); PPI targets H+/K+-ATPase; amoxicillin targets bacterial cell wall; clarithromycin targets bacterial ribosome |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antibiotic combination therapy with acid suppression class)
- Infante, Javier Molina, M.D. · 1 drug in this class
- National Taiwan University Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). PPI, amoxicillin, metronidazole and clarithromycin — Competitive Intelligence Brief. https://druglandscape.com/ci/ppi-amoxicillin-metronidazole-and-clarithromycin. Accessed 2026-05-16.
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