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PP1M — Competitive Intelligence Brief
phase 3
PDE10 inhibitor
PDE10A
Neurology/Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
PP1M (PP1M) — Janssen Research & Development, LLC. PP1M is a phosphodiesterase 10 (PDE10) inhibitor that increases intracellular cyclic nucleotide levels to modulate neuronal signaling.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| PP1M TARGET | PP1M | Janssen Research & Development, LLC | phase 3 | PDE10 inhibitor | PDE10A | |
| ODM-203 (Period 1) | ODM-203 (Period 1) | Orion Corporation, Orion Pharma | marketed | PDE10A inhibitor | PDE10A (phosphodiesterase 10A) | |
| LY2062430 | LY2062430 | Eli Lilly and Company | phase 3 | PDE10A inhibitor | PDE10A (Phosphodiesterase 10A) | |
| E3810 | E3810 | Eisai Co., Ltd. | phase 3 | PDE10A inhibitor | PDE10A (Phosphodiesterase 10A) | |
| DMB-3115 | DMB-3115 | Dong-A ST Co., Ltd. | phase 3 | PDE10A inhibitor | PDE10A | |
| JNJ-77242113 | JNJ-77242113 | Janssen Research & Development, LLC | phase 3 | Phosphodiesterase 10A (PDE10A) inhibitor | PDE10A | |
| Lumateperone high dose | Lumateperone high dose | Intra-Cellular Therapies, Inc. | phase 3 | 5-HT7 receptor antagonist / PDE10 inhibitor | 5-HT7 receptor, PDE10 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (PDE10 inhibitor class)
- Janssen Research & Development, LLC · 1 drug in this class
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Cite this brief
Drug Landscape (2026). PP1M — Competitive Intelligence Brief. https://druglandscape.com/ci/pp1m. Accessed 2026-05-13.
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