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Postop acetaminophen IV — Competitive Intelligence Brief
marketed
Non-opioid analgesic; antipyretic
Cyclooxygenase (COX) enzymes
Pain Management
Small molecule
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Target snapshot
Postop acetaminophen IV (Postop acetaminophen IV) — AdventHealth. Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Postop acetaminophen IV TARGET | Postop acetaminophen IV | AdventHealth | marketed | Non-opioid analgesic; antipyretic | Cyclooxygenase (COX) enzymes | |
| BENZHYDROCODONE | BENZHYDROCODONE | marketed | Opioid analgesic combination; full mu-opioid agonist with non-opioid analgesic | Mu-opioid receptors (primary); delta and kappa opioid receptors (secondary); central nervous system pain pathways | 2018-01-01 | |
| néfopam | néfopam | University Hospital, Bordeaux | marketed | Non-opioid analgesic; monoamine reuptake inhibitor | Norepinephrine transporter (NET); dopamine transporter (DAT); serotonin transporter (SERT) | |
| Per Os Acetaminophen | Per Os Acetaminophen | Hospital for Special Surgery, New York | marketed | Non-opioid analgesic and antipyretic | Cyclooxygenase (COX), primarily in central nervous system | |
| Nefopam administration and prelevment | Nefopam administration and prelevment | University Hospital, Rouen | marketed | Non-opioid analgesic; monoamine reuptake inhibitor | Norepinephrine transporter, dopamine transporter, serotonin transporter | |
| Nefopam ampule | Nefopam ampule | Ministry Of Health / Nineveh Health Directorate | phase 3 | Non-opioid analgesic; monoamine reuptake inhibitor | Norepinephrine transporter, dopamine transporter, serotonin transporter | |
| hydrocodone / acetaminophen extended release | hydrocodone / acetaminophen extended release | Abbott | phase 3 | Opioid agonist / non-opioid analgesic | Opioid receptors |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Non-opioid analgesic; antipyretic class)
- AdventHealth · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Postop acetaminophen IV — Competitive Intelligence Brief. https://druglandscape.com/ci/postop-acetaminophen-iv. Accessed 2026-06-09.
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