Who are post-transplantation cyclophosphamide's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Paraplatin, Cytoxan (Lyophilized), Cyclophosphamide and glucocorticoids, IFO, pirarubicin and cyclophosphamide, Treosulfan (Treo).

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Last reviewed 2026-05-16 · How we verify

post-transplantation cyclophosphamide — Competitive Intelligence Brief

post-transplantation cyclophosphamide (post-transplantation cyclophosphamide) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Alkylating agent. Area: Oncology / Immunology.

marketed Alkylating agent Oncology / Immunology Small molecule Live · refreshed every 30 min

Target snapshot

post-transplantation cyclophosphamide (post-transplantation cyclophosphamide) — Peking University People's Hospital. Post-transplantation cyclophosphamide selectively eliminates alloreactive T cells after hematopoietic stem cell transplantation to reduce graft-versus-host disease while preserving graft-versus-leukemia effects.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
post-transplantation cyclophosphamide TARGET	post-transplantation cyclophosphamide	Peking University People's Hospital	marketed	Alkylating agent
Paraplatin	Carboplatin	MYLAN SEIYAKU Ltd	marketed	Platinum-containing alkylating agent	DNA	1989-01-01
Cytoxan (Lyophilized)	cyclophosphamide	Baxter	marketed	Alkylating agent	Tumor cell DNA	1959-01-01
Cyclophosphamide and glucocorticoids	Cyclophosphamide and glucocorticoids	Peking Union Medical College Hospital	marketed	Alkylating agent + corticosteroid combination
IFO	IFO	Italian Sarcoma Group	marketed	Alkylating Agent	DNA
pirarubicin and cyclophosphamide	pirarubicin and cyclophosphamide	Hebei Medical University Fourth Hospital	marketed	Anthracycline and alkylating agent combination	DNA (topoisomerase II for pirarubicin; DNA alkylation for cyclophosphamide)
Treosulfan (Treo)	Treosulfan (Treo)	Federal Research Institute of Pediatric Hematology, Oncology and Immunology	marketed	Alkylating agent	DNA

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2035-06-26 — Cytoxan (Lyophilized) · 9662342 · Formulation · US
2035-07-13 — Cytoxan (Lyophilized) · 10849916 · Formulation · US
2035-12-01 — Cytoxan (Lyophilized) · 11382923 · Formulation · US
2036-02-15 — Cytoxan (Lyophilized) · 12329767 · Formulation · US
2036-02-15 — Cytoxan (Lyophilized) · 10993952 · Formulation · US

Sponsor landscape (Alkylating agent class)

Assistance Publique - Hôpitaux de Paris · 2 drugs in this class
M.D. Anderson Cancer Center · 2 drugs in this class
Nanfang Hospital, Southern Medical University · 2 drugs in this class
Asahi Kasei Pharma Corporation · 1 drug in this class
Baxter · 1 drug in this class
BeBetter Med Inc · 1 drug in this class
Astellas Pharma China, Inc. · 1 drug in this class
Children's Cancer Group, China · 1 drug in this class
Federal Research Institute of Pediatric Hematology, Oncology and Immunology · 1 drug in this class
Celyad Oncology SA · 1 drug in this class

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Cite this brief

Drug Landscape (2026). post-transplantation cyclophosphamide — Competitive Intelligence Brief. https://druglandscape.com/ci/post-transplantation-cyclophosphamide. Accessed 2026-05-16.

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