Who are PLX-200's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): SPI-2012, Utidelone plus Intermittent Capecitabine.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Subscribe to /feed/ci/plx-200.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-14 · How we verify

PLX-200 — Competitive Intelligence Brief

PLX-200 (PLX-200) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: PLK1 inhibitor. Area: Oncology.

phase 3 PLK1 inhibitor PLK1 (Polo-like kinase 1) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

PLX-200 (PLX-200) — Polaryx Therapeutics, Inc.. PLX-200 is a selective inhibitor of polo-like kinase 1 (PLK1) that disrupts cell cycle progression and induces apoptosis in cancer cells.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
PLX-200 TARGET	PLX-200	Polaryx Therapeutics, Inc.	phase 3	PLK1 inhibitor	PLK1 (Polo-like kinase 1)
SPI-2012	SPI-2012	Spectrum Pharmaceuticals, Inc	phase 3	PLK1 inhibitor	PLK1 (Polo-like kinase 1)
Utidelone plus Intermittent Capecitabine	Utidelone plus Intermittent Capecitabine	Sun Yat-sen University	phase 3	Plk1 inhibitor	Plk1

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (PLK1 inhibitor class)

Polaryx Therapeutics, Inc. · 1 drug in this class
Spectrum Pharmaceuticals, Inc · 1 drug in this class

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Cite this brief

Drug Landscape (2026). PLX-200 — Competitive Intelligence Brief. https://druglandscape.com/ci/plx-200. Accessed 2026-05-14.

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