Who are placebo to vorinostat's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Low dose valproate, Chidamide+ Fulvestrant, Vorinostat (VOR), Romidepsin + CHOP, Tucidinostat, Azacitidine combined with CHOP, Purinostat Mesylate for Injection.

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Last reviewed 2026-05-18 · How we verify

placebo to vorinostat — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

placebo to vorinostat (placebo to vorinostat) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Histone deacetylase inhibitor. Area: Oncology.

phase 3 Histone deacetylase inhibitor Histone deacetylases Oncology Small molecule Live · refreshed every 30 min

Target snapshot

placebo to vorinostat (placebo to vorinostat) — Merck Sharp & Dohme LLC. Vorinostat is a histone deacetylase inhibitor that works by blocking the action of histone deacetylases, leading to the accumulation of acetylated histones and altered gene expression.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
placebo to vorinostat TARGET	placebo to vorinostat	Merck Sharp & Dohme LLC	phase 3	Histone deacetylase inhibitor	Histone deacetylases
Low dose valproate	Low dose valproate	Mario Negri Institute for Pharmacological Research	marketed	Histone deacetylase (HDAC) inhibitor	Histone deacetylases (HDACs)
Chidamide+ Fulvestrant	Chidamide+ Fulvestrant	Liaoning Cancer Hospital & Institute	marketed	HDAC inhibitor + selective estrogen receptor degrader (combination therapy)	Histone deacetylases (HDAC) + Estrogen receptor alpha (ERα)
Vorinostat (VOR)	Vorinostat (VOR)	University of North Carolina, Chapel Hill	marketed	Histone deacetylase (HDAC) inhibitor	Histone deacetylases (HDAC1, HDAC2, HDAC3, HDAC6, HDAC8)
Romidepsin + CHOP	Romidepsin + CHOP	The Lymphoma Academic Research Organisation	phase 3	HDAC inhibitor + chemotherapy combination	Histone deacetylases (HDAC)
Tucidinostat, Azacitidine combined with CHOP	Tucidinostat, Azacitidine combined with CHOP	Peking Union Medical College Hospital	phase 3	Histone deacetylase inhibitor and hypomethylating agent, chemotherapy regimen	Histone deacetylases, DNA methyltransferases
Purinostat Mesylate for Injection	Purinostat Mesylate for Injection	Chengdu Zenitar Biomedical Technology Co., Ltd	phase 3	Histone deacetylase inhibitor	Histone deacetylases

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Histone deacetylase inhibitor class)

Celgene · 1 drug in this class
Chengdu Zenitar Biomedical Technology Co., Ltd · 1 drug in this class
Evopoint Biosciences Inc. · 1 drug in this class
Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
Medical University of Vienna · 1 drug in this class
Merck Sharp & Dohme LLC · 1 drug in this class
NCIC Clinical Trials Group · 1 drug in this class
PharmaMar · 1 drug in this class
Telik · 1 drug in this class
Tianjin Medical University Cancer Institute and Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). placebo to vorinostat — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-to-vorinostat. Accessed 2026-05-18.

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