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Placebo to Raltegravir — Competitive Intelligence Brief
phase 3
Integrase strand transfer inhibitor (INSTI)
HIV integrase
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Placebo to Raltegravir (Placebo to Raltegravir) — Merck Sharp & Dohme LLC. Raltegravir is an integrase strand transfer inhibitor that blocks HIV integrase, preventing the virus from inserting its genetic material into the host cell's DNA.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Placebo to Raltegravir TARGET | Placebo to Raltegravir | Merck Sharp & Dohme LLC | phase 3 | Integrase strand transfer inhibitor (INSTI) | HIV integrase | |
| Switch to B/F/TAF | Switch to B/F/TAF | University of Nairobi | marketed | Antiretroviral combination (integrase inhibitor + nucleoside/nucleotide reverse transcriptase inhibitors) | HIV integrase, HIV reverse transcriptase | |
| Bictegravir (BIC) | Bictegravir (BIC) | National Institute of Allergy and Infectious Diseases (NIAID) | marketed | Integrase strand transfer inhibitor (INSTI) | HIV integrase | |
| Switch to DTG + 3TC | Switch to DTG + 3TC | Hospitales Universitarios Virgen del Rocío | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Dolutegravir / Lamivudine Pill | Dolutegravir / Lamivudine Pill | Charlotte-Paige Rolle, MD | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Cabotegravir Injectable Suspension | Cabotegravir Injectable Suspension | ViiV Healthcare | marketed | Integrase strand transfer inhibitor (INSTI) | HIV integrase | |
| BIC/FTC/TAF | BIC/FTC/TAF | Prism Health North Texas | marketed | Antiretroviral combination therapy (integrase inhibitor + nucleoside reverse transcriptase inhibitors) | HIV integrase, HIV reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Integrase strand transfer inhibitor (INSTI) class)
- ViiV Healthcare · 12 drugs in this class
- National Institute of Allergy and Infectious Diseases (NIAID) · 5 drugs in this class
- Merck Sharp & Dohme LLC · 5 drugs in this class
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal · 1 drug in this class
- Germans Trias i Pujol Hospital · 1 drug in this class
- Groupe d'Etude sur le Risque d'Exposition des Soignants aux Agents Infectieux · 1 drug in this class
- ANRS, Emerging Infectious Diseases · 1 drug in this class
- Massachusetts General Hospital · 1 drug in this class
- University of Colorado, Denver · 1 drug in this class
- MU-JHU CARE · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Placebo to Raltegravir — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-to-raltegravir. Accessed 2026-05-17.
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