Who are Placebo plus Lithium's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Lithobid, Tegretol, CARBAMAZEPINE, Lithium / Fluoxetine, Valproic acid, sodium salt, Lamictal TM.

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Last reviewed 2026-05-15 · How we verify

Placebo plus Lithium — Competitive Intelligence Brief

Placebo plus Lithium (Placebo plus Lithium) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Mood stabilizer. Area: Psychiatry.

marketed Mood stabilizer GSK-3 (glycogen synthase kinase-3), inositol monophosphatase Psychiatry Small molecule Live · refreshed every 30 min

Target snapshot

Placebo plus Lithium (Placebo plus Lithium) — Shanghai Mental Health Center. Lithium modulates intracellular signaling pathways, particularly inhibiting glycogen synthase kinase-3 (GSK-3) and affecting monoamine neurotransmitter systems to stabilize mood.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Placebo plus Lithium TARGET	Placebo plus Lithium	Shanghai Mental Health Center	marketed	Mood stabilizer	GSK-3 (glycogen synthase kinase-3), inositol monophosphatase
Lithobid	lithium carbonate	Generic (multiple manufacturers)	marketed	Mood stabilizer	Inositol-1(or 4)-monophosphatase 1, Glycogen synthase kinase-3	1970-04-06
Tegretol	carbamazepine	Novartis AG (originally Geigy)	marketed	Mood Stabilizer [EPC]	Frizzled-8, Nuclear receptor subfamily 1 group I member 2, Neuronal acetylcholine receptor; alpha2/beta4	1968-03-11
CARBAMAZEPINE	CARBAMAZEPINE		marketed	Mood Stabilizer [EPC]		1968-01-01
Lithium / Fluoxetine	Lithium / Fluoxetine	University of Pennsylvania	marketed	SSRI + mood stabilizer combination	Serotonin transporter (SERT); inositol monophosphatase
Valproic acid, sodium salt	Valproic acid, sodium salt	Sanofi	marketed	Histone deacetylase inhibitor; anticonvulsant; mood stabilizer	Histone deacetylase (HDAC); GABA metabolism
Lamictal TM	Lamictal TM	Central Mental Clinic for Outpatients of Baku City	marketed	Anticonvulsant / Mood stabilizer	Voltage-gated sodium channels; glutamate release inhibition

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2028-11-10 — Tegretol · 9770407 · Formulation · US
2028-11-10 — Tegretol · 9629797 · Method of Use · US
2029-03-13 — Tegretol · 9750822 · Formulation · US
2029-03-13 — Tegretol · 7635773 · Formulation · US
2029-03-13 — Tegretol · 8410077 · Formulation · US
2033-02-27 — Tegretol · 9493582 · Formulation · US
2040-01-31 — Tegretol · 11529357 · Formulation · US

Sponsor landscape (Mood stabilizer class)

Shanghai Mental Health Center · 2 drugs in this class
Generic (multiple manufacturers) · 1 drug in this class
National Cheng-Kung University Hospital · 1 drug in this class
AstraZeneca · 1 drug in this class
University of Aarhus · 1 drug in this class
University of Milan · 1 drug in this class
Weill Medical College of Cornell University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Placebo plus Lithium — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-plus-lithium. Accessed 2026-05-15.

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