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Placebo, Palonosetron, Dexamethasone — Competitive Intelligence Brief

Placebo, Palonosetron, Dexamethasone (Placebo, Palonosetron, Dexamethasone) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: 5-HT3 receptor antagonist + corticosteroid combination. Area: Oncology (supportive care).

phase 3 5-HT3 receptor antagonist + corticosteroid combination 5-HT3 receptor (palonosetron); glucocorticoid receptor (dexamethasone) Oncology (supportive care) Small molecule Live · refreshed every 30 min

Target snapshot

Placebo, Palonosetron, Dexamethasone (Placebo, Palonosetron, Dexamethasone) — Azienda Ospedaliera di Perugia. This is a combination regimen using palonosetron (a 5-HT3 antagonist) and dexamethasone (a corticosteroid) to prevent chemotherapy-induced nausea and vomiting, with placebo as a control arm.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Placebo, Palonosetron, Dexamethasone TARGET Placebo, Palonosetron, Dexamethasone Azienda Ospedaliera di Perugia phase 3 5-HT3 receptor antagonist + corticosteroid combination 5-HT3 receptor (palonosetron); glucocorticoid receptor (dexamethasone)
ramosetron, ondansetron, dexamethasone ramosetron, ondansetron, dexamethasone Government Medical College, Haldwani marketed 5-HT3 receptor antagonist + corticosteroid combination 5-HT3 receptor (ramosetron, ondansetron); glucocorticoid receptor (dexamethasone)
Granisetron and dexamethasone Granisetron and dexamethasone Guangxi Medical University phase 3 5-HT3 receptor antagonist + corticosteroid combination 5-HT3 receptor (granisetron); glucocorticoid receptor (dexamethasone)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (5-HT3 receptor antagonist + corticosteroid combination class)

  1. Azienda Ospedaliera di Perugia · 1 drug in this class
  2. Government Medical College, Haldwani · 1 drug in this class
  3. Guangxi Medical University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Placebo, Palonosetron, Dexamethasone — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-palonosetron-dexamethasone. Accessed 2026-05-17.

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