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Placebo matching depemokimab — Competitive Intelligence Brief
phase 3
IL-4 receptor antagonist monoclonal antibody
IL-4Rα (Interleukin-4 receptor alpha)
Immunology / Allergy / Respiratory
Small molecule
Live · refreshed every 30 min
Target snapshot
Placebo matching depemokimab (Placebo matching depemokimab) — GlaxoSmithKline. Depemokimab is a monoclonal antibody that inhibits interleukin-4 receptor alpha (IL-4Rα) to reduce type 2 inflammatory responses.
Comparator set (5 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Placebo matching depemokimab TARGET | Placebo matching depemokimab | GlaxoSmithKline | phase 3 | IL-4 receptor antagonist monoclonal antibody | IL-4Rα (Interleukin-4 receptor alpha) | |
| Dupilumab - Dose Reduction | Dupilumab - Dose Reduction | Johns Hopkins University | marketed | IL-4 receptor antagonist monoclonal antibody | IL-4 receptor alpha (IL-4Rα) | |
| Dupilumab Injectable Product | Dupilumab Injectable Product | University of Virginia | marketed | IL-4 receptor antagonist monoclonal antibody | IL-4 receptor alpha (IL-4Rα) | |
| Dupilumab (SAR231893) | Dupilumab (SAR231893) | Sanofi | marketed | IL-4 receptor antagonist monoclonal antibody | IL-4 receptor alpha (IL-4Rα) | |
| Dupilumab step-down | Dupilumab step-down | Nantes University Hospital | marketed | IL-4 receptor antagonist monoclonal antibody | IL-4 receptor alpha (IL-4Rα) | |
| Depemokimab (GSK3511294) | Depemokimab (GSK3511294) | GlaxoSmithKline | phase 3 | IL-4 receptor antagonist monoclonal antibody | IL-4Rα (Interleukin-4 receptor alpha) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (IL-4 receptor antagonist monoclonal antibody class)
- GlaxoSmithKline · 2 drugs in this class
- Johns Hopkins University · 1 drug in this class
- Nantes University Hospital · 1 drug in this class
- Sanofi · 1 drug in this class
- University of Virginia · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Placebo matching depemokimab — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-matching-depemokimab. Accessed 2026-05-16.
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