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Placebo matched phentermine/topiramate — Competitive Intelligence Brief
phase 3
Sympathomimetic amine + anticonvulsant combination
Norepinephrine release (phentermine); carbonic anhydrase, GABA receptors, glutamate receptors (topiramate)
Obesity/Weight Management
Small molecule
Live · refreshed every 30 min
Target snapshot
Placebo matched phentermine/topiramate (Placebo matched phentermine/topiramate) — VIVUS LLC. Phentermine/topiramate is a combination that suppresses appetite through sympathomimetic stimulation and enhances satiety through carbonic anhydrase inhibition and GABAergic effects.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Placebo matched phentermine/topiramate TARGET | Placebo matched phentermine/topiramate | VIVUS LLC | phase 3 | Sympathomimetic amine + anticonvulsant combination | Norepinephrine release (phentermine); carbonic anhydrase, GABA receptors, glutamate receptors (topiramate) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Sympathomimetic amine + anticonvulsant combination class)
- VIVUS LLC · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Placebo matched phentermine/topiramate — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-matched-phentermine-topiramate. Accessed 2026-05-17.
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