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Placebo Lonafarnib — Competitive Intelligence Brief

Placebo Lonafarnib (Placebo Lonafarnib) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Farnesyltransferase inhibitor. Area: Oncology.

phase 3 Farnesyltransferase inhibitor Farnesyltransferase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Placebo Lonafarnib (Placebo Lonafarnib) — Eiger BioPharmaceuticals. Lonafarnib inhibits farnesyltransferase, blocking the post-translational modification of proteins involved in cell proliferation and survival.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Placebo Lonafarnib TARGET Placebo Lonafarnib Eiger BioPharmaceuticals phase 3 Farnesyltransferase inhibitor Farnesyltransferase
Zokinvy LONAFARNIB Sentynl Theraps Inc marketed Farnesyltransferase Inhibitor [EPC] farnesyltransferase 2020-01-01
Tipifarnib;Zarnestra; R115777 Tipifarnib;Zarnestra; R115777 Johnson & Johnson Pharmaceutical Research & Development, L.L.C. phase 3 Farnesyltransferase inhibitor Farnesyltransferase
Gemcitabine with R115777 Gemcitabine with R115777 Johnson & Johnson Pharmaceutical Research & Development, L.L.C. phase 3 Nucleoside analog + farnesyltransferase inhibitor combination Ribonucleotide reductase (gemcitabine); farnesyltransferase (R115777)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Farnesyltransferase inhibitor class)

  1. Eiger BioPharmaceuticals · 1 drug in this class
  2. Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Placebo Lonafarnib — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-lonafarnib. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing