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Placebo Combined With Ursodeoxycholic Acid — Competitive Intelligence Brief
phase 3
Bile acid
Farnesoid X receptor (FXR), TGR5
Gastroenterology
Small molecule
Live · refreshed every 30 min
Target snapshot
Placebo Combined With Ursodeoxycholic Acid (Placebo Combined With Ursodeoxycholic Acid) — Xijing Hospital of Digestive Diseases. Ursodeoxycholic acid increases bile flow and reduces cholesterol saturation in bile to prevent gallstone formation and improve biliary function.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Placebo Combined With Ursodeoxycholic Acid TARGET | Placebo Combined With Ursodeoxycholic Acid | Xijing Hospital of Digestive Diseases | phase 3 | Bile acid | Farnesoid X receptor (FXR), TGR5 | |
| Livmarli | maralixibat hydrochloride | Mirum Pharma Inc | marketed | Ileal Bile Acid Transporter Inhibitor | Ileal sodium/bile acid cotransporter | 2021-01-01 |
| Bylvay | ODEVIXIBAT | Ipsen | marketed | Ileal Bile Acid Transporter Inhibitor [EPC] | Ileal sodium/bile acid cotransporter | 2021-01-01 |
| Cholbam | CHOLIC ACID | Mirum | marketed | Bile Acid [EPC] | G-protein coupled bile acid receptor 1 | 2015-01-01 |
| Welchol | COLESEVELAM | Cosette | marketed | Bile Acid Sequestrant | 2000-01-01 | |
| Actigall | URSODIOL | AbbVie | marketed | Bile Acid [EPC] | CDGSH iron-sulfur domain-containing protein 1 | 1987-01-01 |
| Chenix | CHENODIOL | marketed | Bile Acid [EPC] | Bile acid receptor | 1983-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Livmarli · 11260053 · US
- — Livmarli · 11376251 · US
- — Livmarli · 11497745 · US
- — Livmarli · 11229647 · US
Sponsor landscape (Bile acid class)
- Beijing Friendship Hospital · 1 drug in this class
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences · 1 drug in this class
- University of Oxford · 1 drug in this class
- Xijing Hospital of Digestive Diseases · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Placebo Combined With Ursodeoxycholic Acid — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-combined-with-ursodeoxycholic-acid. Accessed 2026-05-16.
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