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Placebo Combined With Ursodeoxycholic Acid — Competitive Intelligence Brief

Placebo Combined With Ursodeoxycholic Acid (Placebo Combined With Ursodeoxycholic Acid) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Bile acid. Area: Gastroenterology.

phase 3 Bile acid Farnesoid X receptor (FXR), TGR5 Gastroenterology Small molecule Live · refreshed every 30 min

Target snapshot

Placebo Combined With Ursodeoxycholic Acid (Placebo Combined With Ursodeoxycholic Acid) — Xijing Hospital of Digestive Diseases. Ursodeoxycholic acid increases bile flow and reduces cholesterol saturation in bile to prevent gallstone formation and improve biliary function.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Placebo Combined With Ursodeoxycholic Acid TARGET Placebo Combined With Ursodeoxycholic Acid Xijing Hospital of Digestive Diseases phase 3 Bile acid Farnesoid X receptor (FXR), TGR5
Livmarli maralixibat hydrochloride Mirum Pharma Inc marketed Ileal Bile Acid Transporter Inhibitor Ileal sodium/bile acid cotransporter 2021-01-01
Bylvay ODEVIXIBAT Ipsen marketed Ileal Bile Acid Transporter Inhibitor [EPC] Ileal sodium/bile acid cotransporter 2021-01-01
Cholbam CHOLIC ACID Mirum marketed Bile Acid [EPC] G-protein coupled bile acid receptor 1 2015-01-01
Welchol COLESEVELAM Cosette marketed Bile Acid Sequestrant 2000-01-01
Actigall URSODIOL AbbVie marketed Bile Acid [EPC] CDGSH iron-sulfur domain-containing protein 1 1987-01-01
Chenix CHENODIOL marketed Bile Acid [EPC] Bile acid receptor 1983-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

Sponsor landscape (Bile acid class)

  1. Beijing Friendship Hospital · 1 drug in this class
  2. Cancer Institute and Hospital, Chinese Academy of Medical Sciences · 1 drug in this class
  3. University of Oxford · 1 drug in this class
  4. Xijing Hospital of Digestive Diseases · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Placebo Combined With Ursodeoxycholic Acid — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-combined-with-ursodeoxycholic-acid. Accessed 2026-05-16.

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