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Placebo Asenapine — Competitive Intelligence Brief
phase 3
Atypical antipsychotic
D2 dopamine receptor, 5-HT2A serotonin receptor
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
Placebo Asenapine (Placebo Asenapine) — Organon and Co. Asenapine is an atypical antipsychotic that blocks dopamine and serotonin receptors in the brain to reduce psychotic symptoms and mood disturbances.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Placebo Asenapine TARGET | Placebo Asenapine | Organon and Co | phase 3 | Atypical antipsychotic | D2 dopamine receptor, 5-HT2A serotonin receptor | |
| Adjunctive asenapine | Adjunctive asenapine | Lori Davis, MD | marketed | Atypical antipsychotic | D2 dopamine receptor, 5-HT2A serotonin receptor | |
| Quetiapine and Topiramate | Quetiapine and Topiramate | University of Cincinnati | marketed | Atypical antipsychotic + anticonvulsant mood stabilizer combination | D2 dopamine receptor, 5-HT2A serotonin receptor (quetiapine); voltage-gated sodium channels, carbonic anhydrase (topiramate) | |
| Asenapine - Double Blind | Asenapine - Double Blind | Organon and Co | phase 3 | Atypical antipsychotic | D2 dopamine receptor, 5-HT2A serotonin receptor | |
| SAMIDORPHAN L-MALATE | SAMIDORPHAN L-MALATE | marketed | Atypical Antipsychotic [EPC] | dopamine and serotonin type 2 (5HT2) receptors, opioid receptors | 2021-01-01 | |
| Lybalvi | SAMIDORPHAN | Alkermes Inc | marketed | Atypical Antipsychotic [EPC] | Mu-type opioid receptor | 2021-01-01 |
| Caplyta | LUMATEPERONE | Intra-Cellular | marketed | Atypical Antipsychotic [EPC] | 5-hydroxytryptamine receptor 2A | 2019-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Lybalvi · 11351166 · US
- — Lybalvi · 11241425 · US
- — Lybalvi · 9126977 · US
- — Lybalvi · 10300054 · US
- — Lybalvi · 10716785 · US
- — Lybalvi · 11185541 · US
- — Lybalvi · 9517235 · US
- — Lybalvi · 9119848 · US
- — Lybalvi · 8778960 · US
Sponsor landscape (Atypical antipsychotic class)
- Shanghai Mental Health Center · 10 drugs in this class
- AstraZeneca · 6 drugs in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 5 drugs in this class
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 4 drugs in this class
- Eli Lilly and Company · 4 drugs in this class
- Otsuka Pharmaceutical Co., Ltd. · 3 drugs in this class
- Medical University of Vienna · 2 drugs in this class
- Organon and Co · 2 drugs in this class
- Chengdu Kanghong Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- H. Lundbeck A/S · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). Placebo Asenapine — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-asenapine. Accessed 2026-05-17.
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