Who are Wakix's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Floxin, Syncurine, Eramin, Betahistine Extended Release formulation, Merislon, Open-label pitolisant.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

How do I get this as a recurring report?

Subscribe to /feed/ci/pitolisant.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-13 · How we verify

Wakix — Competitive Intelligence Brief

Wakix (PITOLISANT) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Area: Neuroscience.

marketed Histamine H3 receptor Neuroscience Small molecule Live · refreshed every 30 min

Target snapshot

Wakix (PITOLISANT) — Harmony. Wakix works by blocking histamine H3 receptors in the brain, allowing more histamine to be available to regulate sleep-wake cycles.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Wakix TARGET	PITOLISANT	Harmony	marketed		Histamine H3 receptor	2019-01-01
Floxin	OFLOXACIN		marketed	Quinolone Antimicrobial [EPC]	Histamine H3 receptor	1990-01-01
Syncurine	DECAMETHONIUM		marketed	decamethonium	Acetylcholinesterase, Histamine H3 receptor, Muscarinic acetylcholine receptor M2	1975-01-01
Eramin	HISTAMINE	Eli Lilly	marketed	histamine	Histamine H3 receptor	1939-01-01
Betahistine Extended Release formulation	Betahistine Extended Release formulation	OBEcure Ltd.	marketed	Histamine H1 receptor agonist / H3 receptor antagonist	Histamine H1 receptor, Histamine H3 receptor
Merislon	Merislon	Zhan Yunfan	marketed		Histamine H3 receptor, Histamine H3 receptor
Open-label pitolisant	Open-label pitolisant	Harmony Biosciences Management, Inc.	phase 3	Histamine H3 receptor antagonist	H3 receptor (histamine H3 receptor)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape

No sponsor landscape data.

Subscribe to ongoing alerts

Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:

Cite this brief

Drug Landscape (2026). Wakix — Competitive Intelligence Brief. https://druglandscape.com/ci/pitolisant. Accessed 2026-05-13.

Build your own brief

Pick any drug + add comparators:

https://druglandscape.com/ci/{slug} — auto-detected competitors
https://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3 — explicit comparators
Brand names auto-resolve: /ci/keytruda → 301 → /ci/pembrolizumab