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Pirfenidone Capsules — Competitive Intelligence Brief
marketed
Antifibrotic agent
TGF-β pathway; multiple pro-fibrotic cytokines
Pulmonology / Respiratory
Small molecule
Live · refreshed every 30 min
Target snapshot
Pirfenidone Capsules (Pirfenidone Capsules) — Shanghai Zhongshan Hospital. Pirfenidone reduces fibroblast proliferation and collagen production by inhibiting multiple pro-fibrotic cytokines and growth factors.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Pirfenidone Capsules TARGET | Pirfenidone Capsules | Shanghai Zhongshan Hospital | marketed | Antifibrotic agent | TGF-β pathway; multiple pro-fibrotic cytokines | |
| pirfenidone or nintedanib | pirfenidone or nintedanib | Hospices Civils de Lyon | marketed | Antifibrotic agent | Pirfenidone: TGF-β pathway; Nintedanib: FGFR, VEGFR, PDGFR tyrosine kinases | |
| pirfenidone 8% gel | pirfenidone 8% gel | Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C. | phase 3 | Antifibrotic agent | TGF-β signaling pathway; fibroblast proliferation | |
| COL-1620 | COL-1620 | Merck KGaA, Darmstadt, Germany | phase 3 | Antifibrotic agent |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antifibrotic agent class)
- Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C. · 1 drug in this class
- Hospices Civils de Lyon · 1 drug in this class
- Merck KGaA, Darmstadt, Germany · 1 drug in this class
- Shanghai Zhongshan Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Pirfenidone Capsules — Competitive Intelligence Brief. https://druglandscape.com/ci/pirfenidone-capsules. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing