Who are Pilocarpine Ophthalmic Solution's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Ecclock, Yupelri, Sanctura, Spiriva, Enablex, Antrenyl.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Pilocarpine Ophthalmic Solution — Competitive Intelligence Brief

Pilocarpine Ophthalmic Solution (Pilocarpine Ophthalmic Solution) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Muscarinic receptor agonist. Area: Ophthalmology.

marketed Muscarinic receptor agonist Muscarinic acetylcholine receptor (M3) Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

Pilocarpine Ophthalmic Solution (Pilocarpine Ophthalmic Solution) — Maastricht University Medical Center. Pilocarpine is a muscarinic acetylcholine receptor agonist that stimulates parasympathetic activity in the eye to increase aqueous humor outflow and reduce intraocular pressure.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Pilocarpine Ophthalmic Solution TARGET	Pilocarpine Ophthalmic Solution	Maastricht University Medical Center	marketed	Muscarinic receptor agonist	Muscarinic acetylcholine receptor (M3)
Ecclock	SOFPIRONIUM BROMIDE	Kaken Pharmaceutical	marketed		Muscarinic acetylcholine receptor M3	2024-01-01
Yupelri	REVEFENACIN	Mylan Ireland Ltd	marketed	Anticholinergic [EPC]	Muscarinic acetylcholine receptor M3	2018-01-01
Sanctura	TROSPIUM	AbbVie	marketed	Cholinergic Muscarinic Antagonist	Muscarinic acetylcholine receptor M3	2004-01-01
Spiriva	TIOTROPIUM BROMIDE	Boehringer Ingelheim	marketed	Anticholinergic	Muscarinic acetylcholine receptor M3	2004-01-01
Enablex	DARIFENACIN	AbbVie	marketed	Cholinergic Muscarinic Antagonist	Muscarinic acetylcholine receptor M3	2004-01-01
Antrenyl	OXYPHENONIUM	Novartis	marketed	oxyphenonium	Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M4	1982-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Muscarinic receptor agonist class)

Allergan · 1 drug in this class
LENZ Therapeutics, Inc · 1 drug in this class
Maastricht University Medical Center · 1 drug in this class
Ocuphire Pharma, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Pilocarpine Ophthalmic Solution — Competitive Intelligence Brief. https://druglandscape.com/ci/pilocarpine-ophthalmic-solution. Accessed 2026-05-14.

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