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Calmatel — Competitive Intelligence Brief
phase 2
Prostaglandin G/H synthase 1, Prostaglandin G/H synthase 2
Pain
Small molecule
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Target snapshot
Calmatel (PIKETOPROFEN).
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Calmatel TARGET | PIKETOPROFEN | phase 2 | Prostaglandin G/H synthase 1, Prostaglandin G/H synthase 2 | |||
| MOFEZOLAC | MOFEZOLAC | marketed | mofezolac | Prostaglandin G/H synthase 1, Prostaglandin G/H synthase 2, Prostaglandin G/H synthase 1 | 1994-01-01 | |
| (+)-Ketoprofen | DEXKETOPROFEN | marketed | Nonsteroidal Anti-inflammatory Drug [EPC] | Prostaglandin G/H synthase 1, Prostaglandin G/H synthase 2 | 1994-01-01 | |
| Profenol | SUPROFEN | Novartis | marketed | suprofen | Cytochrome P450 2C9, Prostaglandin G/H synthase 1, Prostaglandin G/H synthase 2 | 1988-01-01 |
| Rengasil | PIRPROFEN | marketed | pirprofen | Prostaglandin G/H synthase 1, Prostaglandin G/H synthase 2 | 1987-01-01 | |
| Ro 205720 | CARPROFEN | Roche | marketed | carprofen | Complement C5, Prostaglandin G/H synthase 1, Prostaglandin G/H synthase 2 | 1987-01-01 |
| Zomiperac | ZOMEPIRAC | marketed | zomepirac | Prostaglandin G/H synthase 1, Prostaglandin G/H synthase 2, Cyclooxygenase | 1980-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
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Cite this brief
Drug Landscape (2026). Calmatel — Competitive Intelligence Brief. https://druglandscape.com/ci/piketoprofen. Accessed 2026-06-10.
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