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Phase 2: Amisulpride — Competitive Intelligence Brief
phase 3
Atypical antipsychotic
Dopamine D2 receptor, Dopamine D3 receptor
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
Phase 2: Amisulpride (Phase 2: Amisulpride) — Shanghai Mental Health Center. Amisulpride is a selective dopamine D2 and D3 receptor antagonist that blocks dopamine signaling in the brain to reduce psychotic symptoms and improve mood.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Phase 2: Amisulpride TARGET | Phase 2: Amisulpride | Shanghai Mental Health Center | phase 3 | Atypical antipsychotic | Dopamine D2 receptor, Dopamine D3 receptor | |
| ropinirole CR-RLS | ropinirole CR-RLS | GlaxoSmithKline | marketed | Dopamine D2/D3 receptor agonist | Dopamine D2 receptor, Dopamine D3 receptor | |
| Ropinirole (Requip) | Ropinirole (Requip) | St. Luke's-Roosevelt Hospital Center | marketed | Dopamine D2/D3 receptor agonist | Dopamine D2 receptor, Dopamine D3 receptor | |
| [11C]raclopride | [11C]raclopride | New York State Psychiatric Institute | marketed | Dopamine D2/D3 receptor antagonist (PET imaging agent) | Dopamine D2 receptor, Dopamine D3 receptor | |
| Raclopride C11 | Raclopride C11 | University of North Carolina, Chapel Hill | marketed | Dopamine D2/D3 receptor antagonist (PET imaging agent) | Dopamine D2 receptor, Dopamine D3 receptor | |
| aripiprazole long acting injectable formulation | aripiprazole long acting injectable formulation | Vanguard Research Group | marketed | Atypical antipsychotic (dopamine partial agonist) | Dopamine D2 receptor, Dopamine D3 receptor | |
| IM aripiprazole once monthly | IM aripiprazole once monthly | University of Utah | marketed | Atypical antipsychotic | Dopamine D2 receptor, Dopamine D3 receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Atypical antipsychotic class)
- Shanghai Mental Health Center · 10 drugs in this class
- AstraZeneca · 6 drugs in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 5 drugs in this class
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 4 drugs in this class
- Eli Lilly and Company · 4 drugs in this class
- Otsuka Pharmaceutical Co., Ltd. · 3 drugs in this class
- Medical University of Vienna · 2 drugs in this class
- Organon and Co · 2 drugs in this class
- Chengdu Kanghong Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- H. Lundbeck A/S · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). Phase 2: Amisulpride — Competitive Intelligence Brief. https://druglandscape.com/ci/phase-2-amisulpride. Accessed 2026-05-13.
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