Who are PF-07038124's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): metformin and roflumilast, Roflumilast Cream 0.3%.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

PF-07038124 — Competitive Intelligence Brief

PF-07038124 (pf-07038124) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Phosphodiesterase-4 inhibitor. Area: Immunology.

discontinued Phosphodiesterase-4 inhibitor Phosphodiesterase-4 (PDE4) Immunology Small molecule Live · refreshed every 30 min

Target snapshot

PF-07038124 (pf-07038124) — Pfizer Inc.. PF-07038124 is a topical PDE4 inhibitor that blocks phosphodiesterase-4 to reduce inflammatory cytokine production in skin immune cells.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
PF-07038124 TARGET	pf-07038124	Pfizer Inc.	discontinued	Phosphodiesterase-4 inhibitor	Phosphodiesterase-4 (PDE4)
metformin and roflumilast	metformin and roflumilast	University Medical Centre Ljubljana	marketed	Combination therapy: biguanide and phosphodiesterase-4 inhibitor	Metformin: mitochondrial glycerophosphate dehydrogenase; Roflumilast: phosphodiesterase-4 (PDE-4)
Roflumilast Cream 0.3%	Roflumilast Cream 0.3%	Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.	phase 3	Phosphodiesterase-4 inhibitor	Phosphodiesterase-4

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Phosphodiesterase-4 inhibitor class)

Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. · 1 drug in this class
Pfizer Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). PF-07038124 — Competitive Intelligence Brief. https://druglandscape.com/ci/pf-07038124. Accessed 2026-05-13.

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