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pexelizumab in conjunction with CABG — Competitive Intelligence Brief

pexelizumab in conjunction with CABG (pexelizumab in conjunction with CABG) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Monoclonal antibody. Area: Cardiovascular.

phase 3 Monoclonal antibody Complement component 5 (C5) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

pexelizumab in conjunction with CABG (pexelizumab in conjunction with CABG) — Alexion Pharmaceuticals, Inc.. Pexelizumab is a monoclonal antibody that inhibits the complement component 5 (C5) to reduce inflammation.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
pexelizumab in conjunction with CABG TARGET pexelizumab in conjunction with CABG Alexion Pharmaceuticals, Inc. phase 3 Monoclonal antibody Complement component 5 (C5)
[89Zr]Zr-crefmirlimab berdoxam 89zr-zr-crefmirlimab-berdoxam Pfizer marketed Radiolabeled Monoclonal Antibody Fibroblast Activation Protein (FAP) Not specified
Venetoclax; Rituximab venetoclax-rituximab Pfizer marketed BCL-2 inhibitor (venetoclax); Monoclonal antibody (rituximab) BCL-2 (venetoclax); CD20 (rituximab) N/A
Hympavzi MARSTACIMAB Pfizer Inc marketed Monoclonal Antibody Factor Xa 2025-01-01
Beyfortus NIRSEVIMAB AstraZeneca marketed Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody [EPC] RSV 2023-01-01
Darzalex daratumumab Johnson & Johnson marketed Monoclonal antibody CD38 2015-01-01
Praxbind IDARUCIZUMAB Boehringer Ingelheim marketed Humanized Monoclonal Antibody Fragment [EPC] dabigatran and its acylglucuronide metabolites 2015-01-01

Recent regulatory actions (last 90 days)

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Monoclonal antibody class)

  1. Pfizer · 7 drugs in this class
  2. argenx · 7 drugs in this class
  3. Johnson & Johnson · 2 drugs in this class
  4. German CLL Study Group · 2 drugs in this class
  5. Amgen · 2 drugs in this class
  6. Hoffmann-La Roche · 2 drugs in this class
  7. Brii Biosciences Limited · 2 drugs in this class
  8. Alexion Pharmaceuticals, Inc. · 2 drugs in this class
  9. Biotest · 2 drugs in this class
  10. Fondazione Italiana Linfomi - ETS · 2 drugs in this class

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Cite this brief

Drug Landscape (2026). pexelizumab in conjunction with CABG — Competitive Intelligence Brief. https://druglandscape.com/ci/pexelizumab-in-conjunction-with-cabg. Accessed 2026-05-16.

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