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Pertuzumab (ZRC-3277) — Competitive Intelligence Brief
phase 3
HER2-targeted monoclonal antibody
HER2 (Human Epidermal Growth Factor Receptor 2)
Oncology
Biologic
Live · refreshed every 30 min
Target snapshot
Pertuzumab (ZRC-3277) (Pertuzumab (ZRC-3277)) — Zydus Lifesciences Limited. Pertuzumab is a monoclonal antibody that binds to HER2 and blocks its dimerization with other HER receptors, preventing cancer cell growth signaling.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Pertuzumab (ZRC-3277) TARGET | Pertuzumab (ZRC-3277) | Zydus Lifesciences Limited | phase 3 | HER2-targeted monoclonal antibody | HER2 (Human Epidermal Growth Factor Receptor 2) | |
| Pertuzumab + trastuzumab | Pertuzumab + trastuzumab | European Organisation for Research and Treatment of Cancer - EORTC | marketed | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| trastuzumab (H) | trastuzumab (H) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | marketed | HER2-targeted monoclonal antibody | HER2 (human epidermal growth factor receptor 2) | |
| Pertuzumab and Trastuzumab | Pertuzumab and Trastuzumab | QuantumLeap Healthcare Collaborative | marketed | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Trastuzumab + Pertuzumab | Trastuzumab + Pertuzumab | Massachusetts General Hospital | marketed | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Herceptin Hylecta® | Herceptin Hylecta® | Biocon Biologics UK PLC | marketed | HER2-targeted monoclonal antibody | HER2 (human epidermal growth factor receptor 2) | |
| PF-05280014 | PF-05280014 | Pfizer | phase 3 | HER2-targeted monoclonal antibody (trastuzumab biosimilar) | HER2 (human epidermal growth factor receptor 2) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (HER2-targeted monoclonal antibody class)
- Spanish Breast Cancer Research Group · 3 drugs in this class
- Hoffmann-La Roche · 2 drugs in this class
- Samsung Bioepis Co., Ltd. · 1 drug in this class
- Biocon Biologics UK PLC · 1 drug in this class
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · 1 drug in this class
- Tanvex BioPharma USA, Inc. · 1 drug in this class
- Zydus Lifesciences Limited · 1 drug in this class
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- Pertuzumab (ZRC-3277) CI watch — RSS
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- Pertuzumab (ZRC-3277) CI watch — JSON
- Pertuzumab (ZRC-3277) alone — RSS
- Whole HER2-targeted monoclonal antibody class — RSS
Cite this brief
Drug Landscape (2026). Pertuzumab (ZRC-3277) — Competitive Intelligence Brief. https://druglandscape.com/ci/pertuzumab-zrc-3277. Accessed 2026-05-16.
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