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Pertuzumab and Trastuzumab — Competitive Intelligence Brief
marketed
HER2-targeted monoclonal antibody combination
HER2 (human epidermal growth factor receptor 2)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Pertuzumab and Trastuzumab (Pertuzumab and Trastuzumab) — QuantumLeap Healthcare Collaborative. Pertuzumab and trastuzumab are monoclonal antibodies that block HER2 signaling in cancer cells by binding to different epitopes of the HER2 receptor, preventing tumor growth and survival.
Comparator set (5 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Pertuzumab and Trastuzumab TARGET | Pertuzumab and Trastuzumab | QuantumLeap Healthcare Collaborative | marketed | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Pertuzumab + trastuzumab | Pertuzumab + trastuzumab | European Organisation for Research and Treatment of Cancer - EORTC | marketed | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Trastuzumab + Pertuzumab | Trastuzumab + Pertuzumab | Massachusetts General Hospital | marketed | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| FDC of Pertuzumab and Trastuzumab SC | FDC of Pertuzumab and Trastuzumab SC | Hoffmann-La Roche | phase 3 | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Pertuzumab and Trastuzumab FDC SC | Pertuzumab and Trastuzumab FDC SC | Hoffmann-La Roche | phase 3 | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Docetaxel combined + Trastuzumab +Pertuzumab | Docetaxel combined + Trastuzumab +Pertuzumab | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | phase 3 | Chemotherapy + HER2-targeted monoclonal antibody combination | HER2 (trastuzumab and pertuzumab); microtubule stabilization (docetaxel) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (HER2-targeted monoclonal antibody combination class)
- Hoffmann-La Roche · 2 drugs in this class
- European Organisation for Research and Treatment of Cancer - EORTC · 1 drug in this class
- Massachusetts General Hospital · 1 drug in this class
- QuantumLeap Healthcare Collaborative · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Pertuzumab and Trastuzumab — Competitive Intelligence Brief. https://druglandscape.com/ci/pertuzumab-and-trastuzumab. Accessed 2026-05-16.
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