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Pertuzumab and Trastuzumab — Competitive Intelligence Brief

Pertuzumab and Trastuzumab (Pertuzumab and Trastuzumab) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: HER2-targeted monoclonal antibody combination. Area: Oncology.

marketed HER2-targeted monoclonal antibody combination HER2 (human epidermal growth factor receptor 2) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Pertuzumab and Trastuzumab (Pertuzumab and Trastuzumab) — QuantumLeap Healthcare Collaborative. Pertuzumab and trastuzumab are monoclonal antibodies that block HER2 signaling in cancer cells by binding to different epitopes of the HER2 receptor, preventing tumor growth and survival.

Comparator set (5 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Pertuzumab and Trastuzumab TARGET Pertuzumab and Trastuzumab QuantumLeap Healthcare Collaborative marketed HER2-targeted monoclonal antibody combination HER2 (human epidermal growth factor receptor 2)
Pertuzumab + trastuzumab Pertuzumab + trastuzumab European Organisation for Research and Treatment of Cancer - EORTC marketed HER2-targeted monoclonal antibody combination HER2 (human epidermal growth factor receptor 2)
Trastuzumab + Pertuzumab Trastuzumab + Pertuzumab Massachusetts General Hospital marketed HER2-targeted monoclonal antibody combination HER2 (human epidermal growth factor receptor 2)
FDC of Pertuzumab and Trastuzumab SC FDC of Pertuzumab and Trastuzumab SC Hoffmann-La Roche phase 3 HER2-targeted monoclonal antibody combination HER2 (human epidermal growth factor receptor 2)
Pertuzumab and Trastuzumab FDC SC Pertuzumab and Trastuzumab FDC SC Hoffmann-La Roche phase 3 HER2-targeted monoclonal antibody combination HER2 (human epidermal growth factor receptor 2)
Docetaxel combined + Trastuzumab +Pertuzumab Docetaxel combined + Trastuzumab +Pertuzumab Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. phase 3 Chemotherapy + HER2-targeted monoclonal antibody combination HER2 (trastuzumab and pertuzumab); microtubule stabilization (docetaxel)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (HER2-targeted monoclonal antibody combination class)

  1. Hoffmann-La Roche · 2 drugs in this class
  2. European Organisation for Research and Treatment of Cancer - EORTC · 1 drug in this class
  3. Massachusetts General Hospital · 1 drug in this class
  4. QuantumLeap Healthcare Collaborative · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Pertuzumab and Trastuzumab — Competitive Intelligence Brief. https://druglandscape.com/ci/pertuzumab-and-trastuzumab. Accessed 2026-05-16.

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