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Perioperative Pregabalin — Competitive Intelligence Brief

Perioperative Pregabalin (Perioperative Pregabalin) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Gabapentinoid; anticonvulsant; anxiolytic analgesic. Area: Pain Management; Perioperative Medicine.

phase 3 Gabapentinoid; anticonvulsant; anxiolytic analgesic Alpha-2-delta-1 subunit of voltage-gated calcium channels Pain Management; Perioperative Medicine Small molecule Live · refreshed every 30 min

Target snapshot

Perioperative Pregabalin (Perioperative Pregabalin) — McMaster University. Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters and thereby decreasing neuropathic pain and anxiety.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Perioperative Pregabalin TARGET Perioperative Pregabalin McMaster University phase 3 Gabapentinoid; anticonvulsant; anxiolytic analgesic Alpha-2-delta-1 subunit of voltage-gated calcium channels
pregabalin capsules pregabalin capsules AstraZeneca marketed Gabapentinoid; anticonvulsant; anxiolytic Alpha-2-delta-1 subunit of voltage-gated calcium channels
Gabapentin Capsules Gabapentin Capsules EpiCept Corporation marketed Anticonvulsant; Gabapentinoid Alpha-2-delta-1 subunit of voltage-gated calcium channels
Standard dose gabapentin Standard dose gabapentin Mario Negri Institute for Pharmacological Research marketed Anticonvulsant; gabapentinoid Alpha-2-delta-1 subunit of voltage-gated calcium channels
Pregabalin add-on therapy Pregabalin add-on therapy Pfizer's Upjohn has merged with Mylan to form Viatris Inc. phase 3 Gabapentinoid Alpha-2-delta-1 subunit of voltage-gated calcium channels
Placebo matched with pregabalin Placebo matched with pregabalin Pfizer's Upjohn has merged with Mylan to form Viatris Inc. phase 3 Gabapentinoid Alpha-2-delta-1 subunit of voltage-gated calcium channels
Neurontin gabapentin Generic (originally Parke-Davis/Pfizer) marketed Gabapentinoid (anticonvulsant/neuropathic pain agent) Large neutral amino acids transporter small subunit 1, Adenosine receptor A1, Alpha-2A adrenergic receptor 1993-12-30

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Gabapentinoid; anticonvulsant; anxiolytic analgesic class)

  1. McMaster University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Perioperative Pregabalin — Competitive Intelligence Brief. https://druglandscape.com/ci/perioperative-pregabalin. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing