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Perioperative mFLOT — Competitive Intelligence Brief

Perioperative mFLOT (Perioperative mFLOT) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Chemotherapy regimen. Area: Oncology.

phase 3 Chemotherapy regimen Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Perioperative mFLOT (Perioperative mFLOT) — Sixth Affiliated Hospital, Sun Yat-sen University. Perioperative mFLOT is a chemotherapy regimen used to treat various types of cancer.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Perioperative mFLOT TARGET Perioperative mFLOT Sixth Affiliated Hospital, Sun Yat-sen University phase 3 Chemotherapy regimen
chemotherapy of mFOLFOX6 or FOLFIRI chemotherapy of mFOLFOX6 or FOLFIRI Xu jianmin marketed Combination chemotherapy regimen Thymidylate synthase (5-FU), DNA topoisomerase I (irinotecan), DNA (oxaliplatin)
Carboplatin, Etoposide, Ifosfamide Carboplatin, Etoposide, Ifosfamide University Hospital Muenster marketed Combination chemotherapy regimen DNA (multiple mechanisms: alkylation, cross-linking, topoisomerase II inhibition)
Dexamethasona, Idarubicine, ARA-C, Methotrexate Dexamethasona, Idarubicine, ARA-C, Methotrexate PETHEMA Foundation marketed Combination chemotherapy regimen
TAC chemotherapy TAC chemotherapy Agendia marketed Chemotherapy regimen (combination)
FLOT FLOT European Organisation for Research and Treatment of Cancer - EORTC marketed Chemotherapy regimen (combination)
CEV chemotherapy CEV chemotherapy Sun Yat-sen University marketed Combination chemotherapy regimen

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Chemotherapy regimen class)

  1. National Research Center for Hematology, Russia · 2 drugs in this class
  2. Asan Medical Center · 1 drug in this class
  3. AstraZeneca · 1 drug in this class
  4. CTI BioPharma · 1 drug in this class
  5. Federation Francophone de Cancerologie Digestive · 1 drug in this class
  6. Guiyang Medical University · 1 drug in this class
  7. Japan Clinical Oncology Group · 1 drug in this class
  8. PETHEMA Foundation · 1 drug in this class
  9. Sixth Affiliated Hospital, Sun Yat-sen University · 1 drug in this class
  10. Trans Tasman Radiation Oncology Group · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Perioperative mFLOT — Competitive Intelligence Brief. https://druglandscape.com/ci/perioperative-mflot. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing