Who are pentoxyphylline (PTX)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Eucrisa, Eucrisa, Stendra, Daliresp, Pletal, Viagra.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

pentoxyphylline (PTX) — Competitive Intelligence Brief

pentoxyphylline (PTX) (pentoxyphylline (PTX)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Phosphodiesterase inhibitor. Area: Cardiovascular.

phase 3 Phosphodiesterase inhibitor Phosphodiesterase Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

pentoxyphylline (PTX) (pentoxyphylline (PTX)) — National Taiwan University Hospital. Pentoxyphylline (PTX) is a methylxanthine derivative that acts as a phosphodiesterase inhibitor, increasing cyclic AMP levels and improving blood flow.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
pentoxyphylline (PTX) TARGET	pentoxyphylline (PTX)	National Taiwan University Hospital	phase 3	Phosphodiesterase inhibitor	Phosphodiesterase
Eucrisa	CRISABOROLE	Anacor Pharms Inc	marketed	Phosphodiesterase 4 Inhibitor [EPC]	Phosphodiesterase 4	2016-01-01
Eucrisa	Crisaborole	Anacor Pharms Inc	marketed	PDE-4 inhibitor	Phosphodiesterase 4 (PDE-4)	2016-01-01
Stendra	AVANAFIL	Vivus Llc	marketed	Phosphodiesterase 5 Inhibitor [EPC]	cGMP-specific 3',5'-cyclic phosphodiesterase	2012-01-01
Daliresp	ROFLUMILAST	Arcutis	marketed	Phosphodiesterase 4 Inhibitor [EPC]	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	2011-01-01
Pletal	CILOSTAZOL	Otsuka	marketed	Phosphodiesterase 3 Inhibitor [EPC]	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	1999-01-01
Viagra	sildenafil	Pfizer Inc.	marketed	PDE5 inhibitor	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, Multidrug resistance-associated protein 5	1998-03-27

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Phosphodiesterase inhibitor class)

Exonhit · 1 drug in this class
IRCCS San Raffaele · 1 drug in this class
National Taiwan University Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). pentoxyphylline (PTX) — Competitive Intelligence Brief. https://druglandscape.com/ci/pentoxyphylline-ptx. Accessed 2026-05-14.

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