Who are pentothal sodium's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Zulresso, Onfi, Lusedra, Campral, Sonata, Suprane.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

pentothal sodium — Competitive Intelligence Brief

pentothal sodium (pentothal sodium) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Barbiturate. Area: Anesthesia, Neurology.

marketed Barbiturate GABA-A receptor Anesthesia, Neurology Small molecule Live · refreshed every 30 min

Target snapshot

pentothal sodium (pentothal sodium) — Ajou University School of Medicine. Pentothal sodium is a barbiturate that enhances inhibitory neurotransmission by potentiating GABA receptors in the central nervous system, leading to sedation, anesthesia, and anticonvulsant effects.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
pentothal sodium TARGET	pentothal sodium	Ajou University School of Medicine	marketed	Barbiturate	GABA-A receptor
Zulresso	BREXANOLONE	Sage Therap	marketed	Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator	GABA-A receptor alpha-1/beta-2/gamma-2	2019-01-01
Onfi	CLOBAZAM	Lundbeck Pharms Llc	marketed	Benzodiazepine [EPC]	GABA-A receptor alpha-1/beta-2/gamma-2	2011-01-01
Lusedra	FOSPROPOFOL		marketed	fospropofol	GABA-A receptor	2008-01-01
Campral	ACAMPROSATE	Allergan/AbbVie	marketed	acamprosate	GABA-A receptor alpha-1/beta-3/gamma-2	2004-01-01
Sonata	ZALEPLON	Pfizer	marketed	gamma-Aminobutyric Acid A Receptor Agonist [EPC]	GABA-A receptor alpha-1/beta-2/gamma-2	1999-01-01
Suprane	DESFLURANE	Baxter	marketed	General Anesthetic [EPC]	GABA-A receptor; anion channel	1992-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2039-09-05 — Onfi · 12403090 · Formulation · US
2039-09-05 — Onfi · 12290597 · Formulation · US
2040-01-31 — Onfi · 11541002 · Formulation · US

Sponsor landscape (Barbiturate class)

Ajou University School of Medicine · 1 drug in this class
Kamuzu University of Health Sciences · 1 drug in this class
Ph Health · 1 drug in this class
PharPoint Research, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). pentothal sodium — Competitive Intelligence Brief. https://druglandscape.com/ci/pentothal-sodium. Accessed 2026-05-14.

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