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Pemetrexed plus Carboplatin or Cisplatin — Competitive Intelligence Brief
phase 3
Antifolate antimetabolite combined with platinum-based chemotherapy
Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase; DNA (platinum agents)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Pemetrexed plus Carboplatin or Cisplatin (Pemetrexed plus Carboplatin or Cisplatin) — Avistone Biotechnology Co., Ltd.. Pemetrexed inhibits multiple folate-dependent enzymes involved in nucleotide synthesis, while carboplatin or cisplatin are platinum-based agents that cross-link DNA, together inducing cancer cell death.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Pemetrexed plus Carboplatin or Cisplatin TARGET | Pemetrexed plus Carboplatin or Cisplatin | Avistone Biotechnology Co., Ltd. | phase 3 | Antifolate antimetabolite combined with platinum-based chemotherapy | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase; DNA (platinum agents) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antifolate antimetabolite combined with platinum-based chemotherapy class)
- Avistone Biotechnology Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Pemetrexed plus Carboplatin or Cisplatin — Competitive Intelligence Brief. https://druglandscape.com/ci/pemetrexed-plus-carboplatin-or-cisplatin. Accessed 2026-05-16.
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