Who are Pemetrexed Disodium Injection's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Pemetrexed + oral folinic acid rescue, Intrathecal injection of pemetrexed, Pemetrexed + cisplatin, Pemetrexed + Cisplatin /Carboplatin, Pemetrexed + carboplatin, nedaplatin+pemetrexed.

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Last reviewed 2026-06-10 · How we verify

Pemetrexed Disodium Injection — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pemetrexed Disodium Injection (Pemetrexed Disodium Injection) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antifolate antimetabolite. Area: Oncology.

phase 3 Antifolate antimetabolite Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Pemetrexed Disodium Injection (Pemetrexed Disodium Injection) — Shanghai Miracogen Inc.. Pemetrexed is a folate antagonist that inhibits multiple enzymes involved in nucleotide synthesis, disrupting DNA and RNA production in cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Pemetrexed Disodium Injection TARGET	Pemetrexed Disodium Injection	Shanghai Miracogen Inc.	phase 3	Antifolate antimetabolite	Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase
Pemetrexed + oral folinic acid rescue	Pemetrexed + oral folinic acid rescue	Radboud University Medical Center	marketed	Antifolate antimetabolite	Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase
Intrathecal injection of pemetrexed	Intrathecal injection of pemetrexed	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	marketed	Antifolate antimetabolite	Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase
Pemetrexed + cisplatin	Pemetrexed + cisplatin	AstraZeneca	phase 3	Antifolate antimetabolite + platinum-based alkylating agent	Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase (pemetrexed); DNA (cisplatin)
Pemetrexed + Cisplatin /Carboplatin	Pemetrexed + Cisplatin /Carboplatin	Jiangsu Hansoh Pharmaceutical Co., Ltd.	phase 3	Antineoplastic agent	Thymidylate synthase, Dihydrofolate reductase, Glycinamide ribonucleotide formyltransferase
Pemetrexed + carboplatin	Pemetrexed + carboplatin	AstraZeneca	phase 3	Antifolate antimetabolite + platinum-based chemotherapy combination	Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase (pemetrexed); DNA (carboplatin)
nedaplatin+pemetrexed	nedaplatin+pemetrexed	Sun Yat-sen University	phase 3	Platinum-based chemotherapy, Antifolate	DNA, Thymidylate synthase, Dihydrofolate reductase, Glycinamide ribonucleotide formyltransferase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antifolate antimetabolite class)

Allist Pharmaceuticals, Inc. · 1 drug in this class
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 1 drug in this class
Mundipharma K.K. · 1 drug in this class
Radboud University Medical Center · 1 drug in this class
Shanghai Miracogen Inc. · 1 drug in this class
The First Affiliated Hospital with Nanjing Medical University · 1 drug in this class
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Pemetrexed Disodium Injection — Competitive Intelligence Brief. https://druglandscape.com/ci/pemetrexed-disodium-injection. Accessed 2026-06-10.

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