Last reviewed · How we verify
Pemetrexed disodium f Injection — Competitive Intelligence Brief
phase 3
Antifolate antimetabolite
Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Pemetrexed disodium f Injection (Pemetrexed disodium f Injection) — Chia Tai Tianqing Pharmaceutical Group Co., Ltd.. Pemetrexed is a folate antagonist that inhibits multiple enzymes involved in nucleotide synthesis, disrupting DNA and RNA production in cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Pemetrexed disodium f Injection TARGET | Pemetrexed disodium f Injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | phase 3 | Antifolate antimetabolite | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase | |
| Intrathecal injection of pemetrexed | Intrathecal injection of pemetrexed | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | marketed | Antifolate antimetabolite | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase | |
| Pemetrexed + oral folinic acid rescue | Pemetrexed + oral folinic acid rescue | Radboud University Medical Center | marketed | Antifolate antimetabolite | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase | |
| Pemetrexed therapy | Pemetrexed therapy | The First Affiliated Hospital with Nanjing Medical University | phase 3 | Antifolate antimetabolite | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase | |
| nedaplatin+pemetrexed | nedaplatin+pemetrexed | Sun Yat-sen University | phase 3 | Platinum-based chemotherapy, Antifolate | DNA, Thymidylate synthase, Dihydrofolate reductase, Glycinamide ribonucleotide formyltransferase | |
| Pemetrexed+carboplatin/Cisplatin | Pemetrexed+carboplatin/Cisplatin | Suzhou Puhe Pharmaceutical Technology Co., LTD | phase 3 | Antifolate antimetabolite + platinum-based chemotherapy combination | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase; DNA (platinum agents) | |
| Pemetrexed+Cisplatin or Carboplatin | Pemetrexed+Cisplatin or Carboplatin | Sichuan Baili Pharmaceutical Co., Ltd. | phase 3 | Antifolate antimetabolite + platinum-based chemotherapy combination | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase; DNA (platinum agents) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antifolate antimetabolite class)
- Allist Pharmaceuticals, Inc. · 1 drug in this class
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 1 drug in this class
- Mundipharma K.K. · 1 drug in this class
- Radboud University Medical Center · 1 drug in this class
- Shanghai Miracogen Inc. · 1 drug in this class
- The First Affiliated Hospital with Nanjing Medical University · 1 drug in this class
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- Pemetrexed disodium f Injection CI watch — RSS
- Pemetrexed disodium f Injection CI watch — Atom
- Pemetrexed disodium f Injection CI watch — JSON
- Pemetrexed disodium f Injection alone — RSS
- Whole Antifolate antimetabolite class — RSS
Cite this brief
Drug Landscape (2026). Pemetrexed disodium f Injection — Competitive Intelligence Brief. https://druglandscape.com/ci/pemetrexed-disodium-f-injection. Accessed 2026-05-17.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab