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Pemetrexed + Cisplatin /Carboplatin — Competitive Intelligence Brief

Pemetrexed + Cisplatin /Carboplatin (Pemetrexed + Cisplatin /Carboplatin) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antineoplastic agent. Area: Oncology.

phase 3 Antineoplastic agent Thymidylate synthase, Dihydrofolate reductase, Glycinamide ribonucleotide formyltransferase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Pemetrexed + Cisplatin /Carboplatin (Pemetrexed + Cisplatin /Carboplatin) — Jiangsu Hansoh Pharmaceutical Co., Ltd.. Pemetrexed is a folate antagonist that inhibits thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase, leading to cell death in rapidly dividing cancer cells. Cisplatin and Carboplatin are platinum-based chemotherapeutic agents that induce DNA crosslinks, causing cell death.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Pemetrexed + Cisplatin /Carboplatin TARGET Pemetrexed + Cisplatin /Carboplatin Jiangsu Hansoh Pharmaceutical Co., Ltd. phase 3 Antineoplastic agent Thymidylate synthase, Dihydrofolate reductase, Glycinamide ribonucleotide formyltransferase
Pemetrexed + oral folinic acid rescue Pemetrexed + oral folinic acid rescue Radboud University Medical Center marketed Antifolate antimetabolite Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase
Intrathecal injection of pemetrexed Intrathecal injection of pemetrexed Union Hospital, Tongji Medical College, Huazhong University of Science and Technology marketed Antifolate antimetabolite Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase
Pemetrexed disodium f Injection Pemetrexed disodium f Injection Chia Tai Tianqing Pharmaceutical Group Co., Ltd. phase 3 Antifolate antimetabolite Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase
Pemetrexed+carboplatin/Cisplatin Pemetrexed+carboplatin/Cisplatin Suzhou Puhe Pharmaceutical Technology Co., LTD phase 3 Antifolate antimetabolite + platinum-based chemotherapy combination Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase; DNA (platinum agents)
Pemetrexed+Cisplatin or Carboplatin Pemetrexed+Cisplatin or Carboplatin Sichuan Baili Pharmaceutical Co., Ltd. phase 3 Antifolate antimetabolite + platinum-based chemotherapy combination Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase; DNA (platinum agents)
Pemetrexed therapy Pemetrexed therapy The First Affiliated Hospital with Nanjing Medical University phase 3 Antifolate antimetabolite Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antineoplastic agent class)

  1. Acrotech Biopharma Inc. · 1 drug in this class
  2. Asan Medical Center · 1 drug in this class
  3. AstraZeneca · 1 drug in this class
  4. Beijing Biostar Pharmaceuticals Co., Ltd. · 1 drug in this class
  5. Cephalon, Inc. · 1 drug in this class
  6. Jiangsu Hansoh Pharmaceutical Co., Ltd. · 1 drug in this class
  7. Seattle Project Corporation · 1 drug in this class
  8. Taiho Pharmaceutical Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Pemetrexed + Cisplatin /Carboplatin — Competitive Intelligence Brief. https://druglandscape.com/ci/pemetrexed-cisplatin-carboplatin. Accessed 2026-05-16.

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