Last reviewed · How we verify
Pemetrexed + Cisplatin /Carboplatin — Competitive Intelligence Brief
Target snapshot
Pemetrexed + Cisplatin /Carboplatin (Pemetrexed + Cisplatin /Carboplatin) — Jiangsu Hansoh Pharmaceutical Co., Ltd.. Pemetrexed is a folate antagonist that inhibits thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase, leading to cell death in rapidly dividing cancer cells. Cisplatin and Carboplatin are platinum-based chemotherapeutic agents that induce DNA crosslinks, causing cell death.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Pemetrexed + Cisplatin /Carboplatin TARGET | Pemetrexed + Cisplatin /Carboplatin | Jiangsu Hansoh Pharmaceutical Co., Ltd. | phase 3 | Antineoplastic agent | Thymidylate synthase, Dihydrofolate reductase, Glycinamide ribonucleotide formyltransferase | |
| Pemetrexed + oral folinic acid rescue | Pemetrexed + oral folinic acid rescue | Radboud University Medical Center | marketed | Antifolate antimetabolite | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase | |
| Intrathecal injection of pemetrexed | Intrathecal injection of pemetrexed | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | marketed | Antifolate antimetabolite | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase | |
| Pemetrexed disodium f Injection | Pemetrexed disodium f Injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | phase 3 | Antifolate antimetabolite | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase | |
| Pemetrexed+carboplatin/Cisplatin | Pemetrexed+carboplatin/Cisplatin | Suzhou Puhe Pharmaceutical Technology Co., LTD | phase 3 | Antifolate antimetabolite + platinum-based chemotherapy combination | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase; DNA (platinum agents) | |
| Pemetrexed+Cisplatin or Carboplatin | Pemetrexed+Cisplatin or Carboplatin | Sichuan Baili Pharmaceutical Co., Ltd. | phase 3 | Antifolate antimetabolite + platinum-based chemotherapy combination | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase; DNA (platinum agents) | |
| Pemetrexed therapy | Pemetrexed therapy | The First Affiliated Hospital with Nanjing Medical University | phase 3 | Antifolate antimetabolite | Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antineoplastic agent class)
- Acrotech Biopharma Inc. · 1 drug in this class
- Asan Medical Center · 1 drug in this class
- AstraZeneca · 1 drug in this class
- Beijing Biostar Pharmaceuticals Co., Ltd. · 1 drug in this class
- Cephalon, Inc. · 1 drug in this class
- Jiangsu Hansoh Pharmaceutical Co., Ltd. · 1 drug in this class
- Seattle Project Corporation · 1 drug in this class
- Taiho Pharmaceutical Co., Ltd. · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- Pemetrexed + Cisplatin /Carboplatin CI watch — RSS
- Pemetrexed + Cisplatin /Carboplatin CI watch — Atom
- Pemetrexed + Cisplatin /Carboplatin CI watch — JSON
- Pemetrexed + Cisplatin /Carboplatin alone — RSS
- Whole Antineoplastic agent class — RSS
Cite this brief
Drug Landscape (2026). Pemetrexed + Cisplatin /Carboplatin — Competitive Intelligence Brief. https://druglandscape.com/ci/pemetrexed-cisplatin-carboplatin. Accessed 2026-05-16.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab