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Pemetrexed + cisplatin — Competitive Intelligence Brief

Pemetrexed + cisplatin (Pemetrexed + cisplatin) competitive landscape: 0 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antifolate antimetabolite + platinum-based alkylating agent. Area: Oncology.

phase 3 Antifolate antimetabolite + platinum-based alkylating agent Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase (pemetrexed); DNA (cisplatin) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Pemetrexed + cisplatin (Pemetrexed + cisplatin) — AstraZeneca. Pemetrexed inhibits multiple folate-dependent enzymes involved in nucleotide synthesis, while cisplatin causes DNA crosslinking; together they disrupt cancer cell division and DNA replication.

Comparator set

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Pemetrexed + cisplatin TARGET Pemetrexed + cisplatin AstraZeneca phase 3 Antifolate antimetabolite + platinum-based alkylating agent Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase (pemetrexed); DNA (cisplatin)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antifolate antimetabolite + platinum-based alkylating agent class)

  1. AstraZeneca · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Pemetrexed + cisplatin — Competitive Intelligence Brief. https://druglandscape.com/ci/pemetrexed-cisplatin. Accessed 2026-06-10.

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