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Pemetrexed+carboplatin/Cisplatin — Competitive Intelligence Brief

Pemetrexed+carboplatin/Cisplatin (Pemetrexed+carboplatin/Cisplatin) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antifolate antimetabolite + platinum-based chemotherapy combination. Area: Oncology.

phase 3 Antifolate antimetabolite + platinum-based chemotherapy combination Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase; DNA (platinum agents) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Pemetrexed+carboplatin/Cisplatin (Pemetrexed+carboplatin/Cisplatin) — Suzhou Puhe Pharmaceutical Technology Co., LTD. Pemetrexed inhibits multiple folate-dependent enzymes to disrupt DNA synthesis, while carboplatin or cisplatin cross-link DNA strands, together inducing cancer cell death.

Comparator set (2 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Pemetrexed+carboplatin/Cisplatin TARGET Pemetrexed+carboplatin/Cisplatin Suzhou Puhe Pharmaceutical Technology Co., LTD phase 3 Antifolate antimetabolite + platinum-based chemotherapy combination Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase; DNA (platinum agents)
Pemetrexed+Cisplatin or Carboplatin Pemetrexed+Cisplatin or Carboplatin Sichuan Baili Pharmaceutical Co., Ltd. phase 3 Antifolate antimetabolite + platinum-based chemotherapy combination Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase; DNA (platinum agents)
Pemetrexed + carboplatin Pemetrexed + carboplatin AstraZeneca phase 3 Antifolate antimetabolite + platinum-based chemotherapy combination Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase (pemetrexed); DNA (carboplatin)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antifolate antimetabolite + platinum-based chemotherapy combination class)

  1. AstraZeneca · 1 drug in this class
  2. Sichuan Baili Pharmaceutical Co., Ltd. · 1 drug in this class
  3. Suzhou Puhe Pharmaceutical Technology Co., LTD · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Pemetrexed+carboplatin/Cisplatin — Competitive Intelligence Brief. https://druglandscape.com/ci/pemetrexed-carboplatin-cisplatin. Accessed 2026-05-16.

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