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Pegylated liposomal doxorubicin hydrochloride — Competitive Intelligence Brief

Pegylated liposomal doxorubicin hydrochloride (Pegylated liposomal doxorubicin hydrochloride) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Anthracycline chemotherapy (liposomal formulation). Area: Oncology.

marketed Anthracycline chemotherapy (liposomal formulation) Topoisomerase II, DNA Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Pegylated liposomal doxorubicin hydrochloride (Pegylated liposomal doxorubicin hydrochloride) — M.D. Anderson Cancer Center. Pegylated liposomal doxorubicin delivers the chemotherapy agent doxorubicin encapsulated in liposomes coated with polyethylene glycol, which intercalates into DNA and inhibits topoisomerase II while reducing cardiotoxicity through prolonged circulation and selective tumor accumulation.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Pegylated liposomal doxorubicin hydrochloride TARGET Pegylated liposomal doxorubicin hydrochloride M.D. Anderson Cancer Center marketed Anthracycline chemotherapy (liposomal formulation) Topoisomerase II, DNA
Cipro ciprofloxacin Bayer AG marketed Fluoroquinolone antibiotic DNA topoisomerase II, DNA gyrase subunit A, DNA gyrase subunit A 1987-10-22
Epirubicin (E) Epirubicin (E) Eye & ENT Hospital of Fudan University marketed Anthracycline topoisomerase II inhibitor Topoisomerase II, DNA
Liposomal daunorubicin Liposomal daunorubicin University of Birmingham phase 3 Anthracycline chemotherapy agent Topoisomerase II, DNA
epirubicin - cyclophosphamide / docetaxel + bevacizumab epirubicin - cyclophosphamide / docetaxel + bevacizumab GBG Forschungs GmbH phase 3 anthracycline antibiotic, alkylating agent, taxane, monoclonal antibody topoisomerase II, DNA, microtubules, VEGF
Daunorubicin or Idarubicin Daunorubicin or Idarubicin Stichting Hemato-Oncologie voor Volwassenen Nederland phase 3 Anthracycline topoisomerase II inhibitor Topoisomerase II, DNA
Epirubicin Injectable Product Epirubicin Injectable Product The First Affiliated Hospital with Nanjing Medical University phase 3 Anthracycline topoisomerase II inhibitor Topoisomerase II, DNA

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

Sponsor landscape (Anthracycline chemotherapy (liposomal formulation) class)

  1. M.D. Anderson Cancer Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Pegylated liposomal doxorubicin hydrochloride — Competitive Intelligence Brief. https://druglandscape.com/ci/pegylated-liposomal-doxorubicin-hydrochloride. Accessed 2026-05-17.

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