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Pegylated interferon alfa-2a + Ribavirin — Competitive Intelligence Brief
marketed
Antiviral combination therapy
Interferon-alpha receptor; Hepatitis C virus RNA-dependent RNA polymerase
Virology/Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Pegylated interferon alfa-2a + Ribavirin (Pegylated interferon alfa-2a + Ribavirin) — University of California, San Francisco. Pegylated interferon alfa-2a activates innate immunity to suppress viral replication, while ribavirin inhibits viral RNA synthesis, together targeting hepatitis C virus.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Pegylated interferon alfa-2a + Ribavirin TARGET | Pegylated interferon alfa-2a + Ribavirin | University of California, San Francisco | marketed | Antiviral combination therapy | Interferon-alpha receptor; Hepatitis C virus RNA-dependent RNA polymerase | |
| Peg interferon + Ribavirin | Peg interferon + Ribavirin | University of Valencia | marketed | Antiviral combination therapy | Interferon-alpha receptor; Hepatitis C virus RNA-dependent RNA polymerase | |
| F: Peg-interferon alpha-2a & Ribavirin | F: Peg-interferon alpha-2a & Ribavirin | Kaohsiung Medical University Chung-Ho Memorial Hospital | marketed | Antiviral combination therapy | Interferon-alpha receptor; Hepatitis C virus RNA-dependent RNA polymerase | |
| Pegylated interferon and ribavirin | Pegylated interferon and ribavirin | Pacific Health Foundation | marketed | Antiviral combination therapy | Interferon-alpha receptor; Hepatitis C virus RNA-dependent RNA polymerase | |
| Peg-IFN + LD RBV for 16 weeks | Peg-IFN + LD RBV for 16 weeks | National Taiwan University Hospital | marketed | Antiviral combination therapy | Interferon alpha receptor; HCV RNA polymerase | |
| NAs+IFN-α | NAs+IFN-α | Beijing 302 Hospital | marketed | Antiviral combination therapy | Hepatitis B virus reverse transcriptase; interferon-alpha receptor signaling | |
| Quadruple therapy | Quadruple therapy | Sherief Abd-Elsalam | marketed | Antiviral combination therapy |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiviral combination therapy class)
- Kaohsiung Medical University Chung-Ho Memorial Hospital · 6 drugs in this class
- National Taiwan University Hospital · 6 drugs in this class
- Casa Sollievo della Sofferenza IRCCS · 1 drug in this class
- Hepatitis Resource Network · 1 drug in this class
- Hospices Civils de Lyon · 1 drug in this class
- MTI Medical Private Limited, Pakistan · 1 drug in this class
- Pacific Health Foundation · 1 drug in this class
- RedHill Biopharma Limited · 1 drug in this class
- Sherief Abd-Elsalam · 1 drug in this class
- The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz) · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Pegylated interferon alfa-2a + Ribavirin — Competitive Intelligence Brief. https://druglandscape.com/ci/pegylated-interferon-alfa-2a-ribavirin. Accessed 2026-05-17.
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