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Cytalux — Competitive Intelligence Brief
marketed
Optical Imaging Agent
Folate receptor alpha
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Cytalux (PAFOLACIANINE) — On Target Labs.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Cytalux TARGET | PAFOLACIANINE | On Target Labs | marketed | Optical Imaging Agent | Folate receptor alpha | 2021-01-01 |
| Alimta | pemetrexed | Actavis | marketed | Folate Analog Metabolic Inhibitor | Folate receptor alpha | 2004-01-01 |
| Flotufolastat (18F) | Flotufolastat (18F) | Blue Earth Diagnostics | marketed | Folate receptor-targeted PET imaging agent | Folate receptor alpha (FR-α) | |
| Cytalux | Cytalux | Ann & Robert H Lurie Children's Hospital of Chicago | marketed | Folate receptor alpha | ||
| Mirvetuximab soravtansine plus Bevacizumab | Mirvetuximab soravtansine plus Bevacizumab | AbbVie | phase 3 | Antibody-drug conjugate (mirvetuximab soravtansine) + monoclonal antibody (bevacizumab) | Folate receptor alpha (FRA) and VEGF | |
| AFOLIA | AFOLIA | Fertility Biotech AG | phase 3 | Folate receptor alpha (FRα) | ||
| OTL38 for Injection | OTL38 for Injection | On Target Laboratories, LLC | phase 3 | Antibody-drug conjugate (ADC) | Folate receptor alpha (FRA) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Alimta · 9604990 · Compound · US
- — Alimta · 12115164 · Method of Use · US
- — Alimta · 11793813 · Formulation · US
Sponsor landscape (Optical Imaging Agent class)
- On Target Labs · 1 drug in this class
- Sun Pharma · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Cytalux — Competitive Intelligence Brief. https://druglandscape.com/ci/pafolacianine. Accessed 2026-05-16.
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