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Paclitaxel (PTX) — Competitive Intelligence Brief
phase 3
Taxane; microtubule-stabilizing agent
β-tubulin (microtubule)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Paclitaxel (PTX) (Paclitaxel (PTX)) — Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections. Paclitaxel stabilizes microtubules by binding to β-tubulin, preventing their depolymerization and causing cell cycle arrest in the G2/M phase, leading to cancer cell death.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Paclitaxel (PTX) TARGET | Paclitaxel (PTX) | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | phase 3 | Taxane; microtubule-stabilizing agent | β-tubulin (microtubule) | |
| Paclitaxel (Pac) | Paclitaxel (Pac) | Aravive, Inc. | marketed | Taxane; microtubule stabilizer | β-tubulin / microtubules | |
| Docetaxel (DOC) | Docetaxel (DOC) | Sun Yat-sen University | marketed | Taxane; microtubule stabilizer | β-tubulin | |
| Standard of Care: Docetaxel | Standard of Care: Docetaxel | H. Lee Moffitt Cancer Center and Research Institute | marketed | Taxane; microtubule stabilizer | β-tubulin | |
| Paclitaxel, Epirubicin | Paclitaxel, Epirubicin | Tianjin Medical University Cancer Institute and Hospital | marketed | Chemotherapy combination (taxane + anthracycline) | Microtubules (paclitaxel); Topoisomerase II and DNA (epirubicin) | |
| Placebo plus Docetaxel | Placebo plus Docetaxel | Infinity Pharmaceuticals, Inc. | marketed | Taxane (microtubule stabilizer) | Microtubules (β-tubulin) | |
| Cabazitaxel (XRP6258) | Cabazitaxel (XRP6258) | Sanofi | marketed | Taxane; microtubule stabilizer | β-tubulin (microtubule) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Taxane; microtubule-stabilizing agent class)
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections · 1 drug in this class
- Hoffmann-La Roche · 1 drug in this class
- M.D. Anderson Cancer Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Paclitaxel (PTX) — Competitive Intelligence Brief. https://druglandscape.com/ci/paclitaxel-ptx. Accessed 2026-05-16.
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