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Paclitaxel (PTX) — Competitive Intelligence Brief

Paclitaxel (PTX) (Paclitaxel (PTX)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Taxane; microtubule-stabilizing agent. Area: Oncology.

phase 3 Taxane; microtubule-stabilizing agent β-tubulin (microtubule) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Paclitaxel (PTX) (Paclitaxel (PTX)) — Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections. Paclitaxel stabilizes microtubules by binding to β-tubulin, preventing their depolymerization and causing cell cycle arrest in the G2/M phase, leading to cancer cell death.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Paclitaxel (PTX) TARGET Paclitaxel (PTX) Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections phase 3 Taxane; microtubule-stabilizing agent β-tubulin (microtubule)
Paclitaxel (Pac) Paclitaxel (Pac) Aravive, Inc. marketed Taxane; microtubule stabilizer β-tubulin / microtubules
Docetaxel (DOC) Docetaxel (DOC) Sun Yat-sen University marketed Taxane; microtubule stabilizer β-tubulin
Standard of Care: Docetaxel Standard of Care: Docetaxel H. Lee Moffitt Cancer Center and Research Institute marketed Taxane; microtubule stabilizer β-tubulin
Paclitaxel, Epirubicin Paclitaxel, Epirubicin Tianjin Medical University Cancer Institute and Hospital marketed Chemotherapy combination (taxane + anthracycline) Microtubules (paclitaxel); Topoisomerase II and DNA (epirubicin)
Placebo plus Docetaxel Placebo plus Docetaxel Infinity Pharmaceuticals, Inc. marketed Taxane (microtubule stabilizer) Microtubules (β-tubulin)
Cabazitaxel (XRP6258) Cabazitaxel (XRP6258) Sanofi marketed Taxane; microtubule stabilizer β-tubulin (microtubule)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Taxane; microtubule-stabilizing agent class)

  1. Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections · 1 drug in this class
  2. Hoffmann-La Roche · 1 drug in this class
  3. M.D. Anderson Cancer Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Paclitaxel (PTX) — Competitive Intelligence Brief. https://druglandscape.com/ci/paclitaxel-ptx. Accessed 2026-05-16.

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