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Paclitaxel, Docetaxel, Irinotecan — Competitive Intelligence Brief
phase 3
Microtubule inhibitor
Microtubules
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Paclitaxel, Docetaxel, Irinotecan (Paclitaxel, Docetaxel, Irinotecan) — Shanghai Hengrui Pharmaceutical Co., Ltd.. Paclitaxel, Docetaxel, and Irinotecan are microtubule inhibitors that work by stabilizing microtubules, thereby inhibiting cell division.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Paclitaxel, Docetaxel, Irinotecan TARGET | Paclitaxel, Docetaxel, Irinotecan | Shanghai Hengrui Pharmaceutical Co., Ltd. | phase 3 | Microtubule inhibitor | Microtubules | |
| Dose dense AC followed by T + trastuzumab | Dose dense AC followed by T + trastuzumab | Agendia | marketed | Chemotherapy regimen with monoclonal antibody | HER2 receptor (trastuzumab component); DNA/microtubules (chemotherapy components) | |
| docetaxel and cisplatin | docetaxel and cisplatin | Sanofi | marketed | Chemotherapy combination (taxane + platinum agent) | Microtubules (docetaxel); DNA (cisplatin) | |
| Ivermectin + colchicine | Ivermectin + colchicine | Ain Shams University | marketed | Antiparasitic + anti-inflammatory combination | Glutamate-gated chloride channels (ivermectin); tubulin/microtubules (colchicine) | |
| Placebo plus Docetaxel | Placebo plus Docetaxel | Infinity Pharmaceuticals, Inc. | marketed | Taxane (microtubule stabilizer) | Microtubules (β-tubulin) | |
| Paclitaxel, Carboplatin | Paclitaxel, Carboplatin | Queensland Centre for Gynaecological Cancer | marketed | Chemotherapy combination (taxane + platinum agent) | Microtubules (paclitaxel); DNA (carboplatin) | |
| nab-paclitaxel,Cisplatin | nab-paclitaxel,Cisplatin | Yang Jianjun, PhD | marketed | Chemotherapy combination (taxane + platinum agent) | Microtubules (paclitaxel); DNA (cisplatin) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Microtubule inhibitor class)
- Ma Fei,MD · 2 drugs in this class
- Eisai Co., Ltd. · 1 drug in this class
- Jiangsu Alphamab Biopharmaceuticals Co., Ltd · 1 drug in this class
- Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
- Nippon Kayaku Co., Ltd. · 1 drug in this class
- Shanghai Hengrui Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Paclitaxel, Docetaxel, Irinotecan — Competitive Intelligence Brief. https://druglandscape.com/ci/paclitaxel-docetaxel-irinotecan. Accessed 2026-05-17.
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