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P2Y12 inhibitor de-escalation — Competitive Intelligence Brief
phase 3
P2Y12 inhibitor
P2Y12 receptor
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
P2Y12 inhibitor de-escalation (P2Y12 inhibitor de-escalation) — Azienda Ospedaliera Universitaria Policlinico "G. Martino". P2Y12 inhibitors block the action of ADP on the P2Y12 receptor, preventing platelet activation and aggregation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| P2Y12 inhibitor de-escalation TARGET | P2Y12 inhibitor de-escalation | Azienda Ospedaliera Universitaria Policlinico "G. Martino" | phase 3 | P2Y12 inhibitor | P2Y12 receptor | |
| Group P+T | Group P+T | Huazhong University of Science and Technology | marketed | P2Y12 inhibitor | P2Y12 receptor | |
| Acetylsalicylic Acid + clopidogrel | Acetylsalicylic Acid + clopidogrel | Hospital Universitari Vall d'Hebron Research Institute | marketed | Dual antiplatelet agent | Cyclooxygenase-1 (COX-1) and P2Y12 receptor | |
| Group P+P | Group P+P | Huazhong University of Science and Technology | marketed | P2Y12 inhibitor | P2Y12 receptor | |
| heparin + clopidogrel + aspirin | heparin + clopidogrel + aspirin | Centre Hospitalier de PAU | marketed | Antiplatelet and anticoagulant combination | Thrombin, Factor Xa, Cyclooxygenase, P2Y12 receptor | |
| prasugrel / clopidogrel | prasugrel / clopidogrel | Assistance Publique - Hôpitaux de Paris | marketed | P2Y12 receptor antagonist (thienopyridine) | P2Y12 receptor | |
| ticagrelor + ASA | ticagrelor + ASA | Peking University Third Hospital | marketed | Dual antiplatelet agent | P2Y12 receptor (ticagrelor); cyclooxygenase (aspirin) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (P2Y12 inhibitor class)
- Huazhong University of Science and Technology · 2 drugs in this class
- Azienda Ospedaliera Universitaria Policlinico "G. Martino" · 1 drug in this class
- Shanghai Jiao Tong University School of Medicine · 1 drug in this class
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Cite this brief
Drug Landscape (2026). P2Y12 inhibitor de-escalation — Competitive Intelligence Brief. https://druglandscape.com/ci/p2y12-inhibitor-de-escalation. Accessed 2026-05-18.
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