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OTL38 for Injection — Competitive Intelligence Brief
phase 3
Antibody-drug conjugate (ADC)
Folate receptor alpha (FRA)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
OTL38 for Injection (OTL38 for Injection) — On Target Laboratories, LLC. OTL38 is a folate receptor alpha-targeted immunoconjugate that delivers a cytotoxic payload to cancer cells expressing folate receptor alpha.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| OTL38 for Injection TARGET | OTL38 for Injection | On Target Laboratories, LLC | phase 3 | Antibody-drug conjugate (ADC) | Folate receptor alpha (FRA) | |
| LONCASTUXIMAB TESIRINE | LONCASTUXIMAB TESIRINE | marketed | Antibody-Drug Conjugate (ADC) | CD19 | 2021-01-01 | |
| Tisotumab Vedotin | tivdak | SEAGEN | marketed | Antibody-Drug Conjugate (ADC) | Tissue factor | 2021-01-01 |
| Besponsa | inotuzumab-ozogamicin | Pfizer | marketed | Antibody-drug conjugate (ADC) | CD22 | 2017-01-01 |
| Mylotarg | Gemtuzumab Ozogamicin | Pfizer | marketed | Antibody-drug conjugate (ADC) | CD33 antigen | 2000-01-01 |
| Herceptin | trastuzumab | Roche | marketed | Antibody-drug conjugate (ADC) | HER2 receptor, subdomain IV | 1998-01-01 |
| Besponsa | Inotuzumab Ozogamicin | Pfizer Inc. | marketed | Antibody-drug conjugate (ADC) | CD22 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antibody-drug conjugate (ADC) class)
- Pfizer · 3 drugs in this class
- Jiaxing AnDiCon Biotech Co.,Ltd · 2 drugs in this class
- AstraZeneca · 1 drug in this class
- BioAtla, Inc. · 1 drug in this class
- Byondis B.V. · 1 drug in this class
- Charite University, Berlin, Germany · 1 drug in this class
- Gustave Roussy, Cancer Campus, Grand Paris · 1 drug in this class
- Medstar Health Research Institute · 1 drug in this class
- OBI Pharma, Inc · 1 drug in this class
- On Target Laboratories, LLC · 1 drug in this class
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Cite this brief
Drug Landscape (2026). OTL38 for Injection — Competitive Intelligence Brief. https://druglandscape.com/ci/otl38-for-injection. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing