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Oteseconazole (VT-1161) — Competitive Intelligence Brief
phase 3
Azole antifungal
Fungal lanosterol 14α-demethylase (CYP51)
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Oteseconazole (VT-1161) (Oteseconazole (VT-1161)) — Mycovia Pharmaceuticals Inc.. Oteseconazole is a selective inhibitor of fungal lanosterol 14α-demethylase (CYP51) that disrupts ergosterol synthesis in fungal cell membranes.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Oteseconazole (VT-1161) TARGET | Oteseconazole (VT-1161) | Mycovia Pharmaceuticals Inc. | phase 3 | Azole antifungal | Fungal lanosterol 14α-demethylase (CYP51) | |
| Vivjoa | OTESECONAZOLE | Mycovia Pharms | marketed | Azole Antifungal [EPC] | Cytochrome P450 3A4 | 2022-01-01 |
| Cresemba | ISAVUCONAZONIUM | Astellas Pharma | marketed | Azole Antifungal | ATP-binding cassette sub-family G member 2 | 2015-01-01 |
| Jublia | EFINACONAZOLE | Bausch Health | marketed | Azole Antifungal [EPC] | 2014-01-01 | |
| Luzu | LULICONAZOLE | Bausch Health | marketed | Azole Antifungal [EPC] | 2013-01-01 | |
| POSACONAZOLE | POSACONAZOLE | marketed | Azole Antifungal [EPC] | 2005-01-01 | ||
| VORICONAZOLE | VORICONAZOLE | marketed | Azole Antifungal [EPC] | 2002-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Azole antifungal class)
- Pfizer · 3 drugs in this class
- Elion Therapeutics, Inc. · 1 drug in this class
- Hadassah Medical Organization · 1 drug in this class
- Hatem AbuHashim · 1 drug in this class
- Janssen Pharmaceutical K.K. · 1 drug in this class
- Jiangsu Aosaikang Pharmaceutical Co., Ltd. · 1 drug in this class
- Military Hospital of Tunis · 1 drug in this class
- Mycovia Pharmaceuticals Inc. · 1 drug in this class
- Nuvation Bio Inc. · 1 drug in this class
- Purdue Pharma LP · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Oteseconazole (VT-1161) — Competitive Intelligence Brief. https://druglandscape.com/ci/oteseconazole-vt-1161. Accessed 2026-05-17.
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