Who are Orlistat (Xenical)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Liraglutide + Orlistat, Xenical, Pegasys, Copegus, liraglutide combined with orlistat.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Orlistat (Xenical) — Competitive Intelligence Brief

Orlistat (Xenical) (Orlistat (Xenical)) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Lipase inhibitor. Area: Obesity/Weight management.

marketed Lipase inhibitor Pancreatic lipase, gastric lipase Obesity/Weight management Small molecule Live · refreshed every 30 min

Target snapshot

Orlistat (Xenical) (Orlistat (Xenical)) — St. Louis University. Orlistat inhibits pancreatic and gastric lipases to reduce the absorption of dietary fats in the gastrointestinal tract.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Orlistat (Xenical) TARGET	Orlistat (Xenical)	St. Louis University	marketed	Lipase inhibitor	Pancreatic lipase, gastric lipase
Liraglutide + Orlistat	Liraglutide + Orlistat	East Carolina University	marketed	GLP-1 receptor agonist + lipase inhibitor combination	GLP-1 receptor; pancreatic and gastric lipases
Xenical, Pegasys, Copegus	Xenical, Pegasys, Copegus	Brooke Army Medical Center	marketed	Antiviral combination therapy (interferon + nucleoside analog); Lipase inhibitor	Hepatitis C virus NS5B polymerase; pancreatic lipase
liraglutide combined with orlistat	liraglutide combined with orlistat	The Fourth Affiliated Hospital of Zhejiang University School of Medicine	marketed	GLP-1 receptor agonist combined with pancreatic lipase inhibitor	GLP-1 receptor (liraglutide); pancreatic and gastric lipases (orlistat)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Lipase inhibitor class)

Empros Pharma AB · 1 drug in this class
St. Louis University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Orlistat (Xenical) — Competitive Intelligence Brief. https://druglandscape.com/ci/orlistat-xenical. Accessed 2026-05-14.

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